A compound preparation for treating pancytopenia and its preparation method

A technology for hemocytopenia and compound preparations, applied in the direction of extracellular fluid diseases, medical raw materials derived from mammals, medical preparations containing active ingredients, etc., can solve problems such as syndrome differentiation, dose dependence, and serious side effects

A technology for hemocytopenia and compound preparations, applied in the direction of extracellular fluid diseases, medical raw materials derived from mammals, medical preparations containing active ingredients, etc., can solve problems such as syndrome differentiation, dose dependence, and serious side effects

CN103893469BActive Publication Date: 2017-05-24陕西中医学院第二附属医院

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  • A compound preparation for treating pancytopenia and its preparation method
  • A compound preparation for treating pancytopenia and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0017] Below by enumerating clinical curative effect observation experiment, specific verification illustrates effect of the present invention.

[0018] 1. Experimental content

[0019] From May 2013 to March 2014, 50 outpatients and inpatients in the Hematology Department of the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine met the inclusion criteria. They were randomly divided into a treatment group of 25 cases and an observation group of 25 cases. Clinical Observation. To comprehensively and systematically evaluate the clinical efficacy of this traditional Chinese medicine compound preparation in the treatment of leukopenia of kidney yin deficiency after chemotherapy.

[0020] 1.1 Diagnostic criteria

[0021] Diagnostic criteria of western medicine: The white blood cell count in "Diagnosis and Curative Effect Standards of Blood Diseases" is less than 4.0×10 for two consecutive times 9 / L.

[0022] TCM diagnostic criteria: According to ...

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Abstract

The invention provides a compound preparation for treating pancytopenia, which is small in toxic and side effect and obvious in treatment effect. The compound preparation is mainly prepared from the following raw medical materials by weight percent: 15% to 18% of bovine bone marrow, 8% to 10% of placenta hominis, 8% to 10% of rehmannia glutinosa, 8% to 10% of Chinese yam, 8% to 10% of lycium barbarum, 8% to 10% of dogwood, 15% to 18% of medicinal cyathula root, 8% to 10% of deerhorn glue, 8% to 10% of semen cuscutae and 8% to 10% of tortoise plastron glue. According to the compound preparation, the functions of an ancient formula 'Zuogui Pill' capable of enriching yin and nourishing kidney as well as replenishing essence and benefiting marrow are utilized; and yang-tonifying medicines are added into the yin-tonifying formula, so that the compound preparation has the functions of enriching yin and nourishing the kidney, replenishing essence and benefiting marrow as well as reinforcing qi and nourishing blood under the formula synergy in manners of reinforcing yang from yin and reinforcing yin from yang.

Description

technical field [0001] The invention belongs to the field of medicine, and is a compound preparation for treating pancytopenia and kidney yin deficiency, mainly suitable for aplastic anemia, acute leukemia, myelodysplastic syndrome, megaloblastic Pancytopenia caused by anemia, immune hemolytic anemia, paroxysmal hemoglobinuria, hypersplenism, primary myelofibrosis, etc. Background technique [0002] Pancytopenia (PCP) is one of the common diseases in the blood system, mainly refers to peripheral blood red blood cell (RBC) or hemoglobin (Hb), white blood cell (WBC), platelet (PLT) counts continue to be lower than the normal range. Clinically, the main manifestations are anemia, hemorrhage, and infection. It can be caused by a variety of etiologies. Pancytopenia is mainly caused by hematopoietic system diseases, and a small part can be caused by non-hematopoietic system diseases. Aplastic anemia, acute leukemia, myelodysplastic syndrome, megaloblastic anemia, immune hemolyti...

Claims

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Application Information

Patent Timeline
24 May 2017
Publication
CN103893469B
IPC
A61K36/8945; A61P7/00; A61P7/06; A61K35/32; A61K35/50; A61K35/28; A61K35/586
Inventors
董昌虎; 何春玲