System and method for enhancing intensity of biological tissue terahertz wave imaging signal
A technology of biological tissue and imaging signals, which is applied in medical science, sensors, diagnostic recording/measurement, etc., can solve the problems of limited penetration depth of pulsed terahertz waves, high purchase and maintenance costs, complex system composition, etc., and achieve simple structure , low price, fast imaging effect
Inactive Publication Date: 2014-07-16
CAPITAL NORMAL UNIVERSITY
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Problems solved by technology
However, the imaging signal intensity of biological tissue and the contrast between different tissues, especially diseased tissue and normal tissue, need to be further improved; at the same time, most of the existing terahertz wave imaging systems for biological tissue are pulsed terahertz wave imaging systems, which have complex system configurations. , high purchase and maintenance costs, slow imaging speed and low stability; and because the water vapor in the air has a large absorption coefficient in the frequency band corresponding to the pulsed terahertz wave, it is difficult for the pulsed terahertz wave imaging system to be practical application; and because biological tissue cells contain a large amount of water, the absorption coefficient of water in the frequency band corresponding to the pulsed terahertz wave is relatively large, resulting in a limited penetration depth of the pulsed terahertz wave in biological tissue
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Embodiment 1
[0027] (1) Use the Gunn oscillator 1 to emit 0.2 THz terahertz waves, which are reflected by the first metal plane mirror 4 to the tumor cell liquid on the translation platform 8 for irradiation, and then reflected by the tumor cell liquid, the second metal plane mirror 5 and the parabolic mirror 7 in turn After reaching the pyroelectric detector 2, the signal strength of the terahertz wave is detected;
[0028] (2) Use femtosecond laser 3 to emit 800nm infrared laser (1.062W / cm 2 ) to irradiate the tumor cell liquid, and use the Gunn oscillator 1 to emit 0.2 THz terahertz waves, which are reflected by the first metal plane mirror 4 to the tumor cell liquid on the translation platform 8 for irradiation, and then pass through the tumor cell liquid and the second metal plane mirror 5 in turn. And after being reflected by the parabolic mirror 7, it reaches the pyroelectric detector 2 to detect the signal intensity of the terahertz wave;
[0029] (3) Directly inject gold nanopa...
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The invention relates to a system and method for enhancing the intensity of a biological tissue terahertz wave imaging signal. The system and method are used for enhancing the intensity of the biological tissue terahertz wave imaging signal and improving the terahertz wave imaging contrast ratio of diseased tissue and normal tissue. The system comprises a terahertz wave generator, a terahertz wave detector, a laser generator, a medium plane mirror, a first metal plane mirror, a second metal plane mirror, a paraboloidal mirror and a horizontal moving platform, a fixed included angle is formed between the back face of the first metal plane mirror and the second metal plane mirror, the first metal plane mirror and the second metal plane mirror are arranged above the horizontal moving platform in a gap mode, the paraboloidal mirror is arranged on the other sides of the two metal plane mirrors, the terahertz wave detector is arranged on one side of the paraboloidal mirror, the medium plane mirror is arranged above gaps of the two metal plane mirrors, and the laser generator is arranged on one side of the medium plane mirror.
Description
technical field [0001] The invention relates to the application field of biological tissue imaging of terahertz waves, in particular to a system and method for enhancing signal intensity of biological tissue terahertz wave imaging. Background technique [0002] Compared with the adjacent infrared and microwaves in the electromagnetic spectrum, terahertz waves have the characteristics of low photon energy, strong penetration, and spectrum coverage of vibration and rotational energy levels of organic and biological macromolecules, and can discover new spectra. Analysis and imaging detection technology has important application prospects in the fields of medical diagnosis and biometrics. And its imaging equipment is simpler and more portable than nuclear magnetic resonance imaging and computerized tomography imaging, and can be used for real-time navigation of medical operations. Terahertz wave imaging, as an emerging means of studying biological tissue properties and imaging ...
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IPC IPC(8): A61B5/00
Inventor 张亮亮张锐吴同张存林
Owner CAPITAL NORMAL UNIVERSITY
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