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A compound medicine for treating pulmonary heart disease and its preparation method and application

A technology for cor pulmonale and drugs, applied in the field of compound medicine for the treatment of cor pulmonale and its preparation, can solve the problems of lack of effective prescriptions for prevention and treatment, and achieve the effect of easy operation, convenient taking, and good curative effect

Active Publication Date: 2017-02-08
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the current traditional Chinese medicine therapy still lacks effective prescriptions for preventing and treating this disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A compound combination medicine for treating cor pulmonale, comprising the following components in parts by weight: Codonopsis 30g, Ophiopogon japonicus 10g, Schisandra chinensis 30g, Chinese yam 30g, Rehmannia glutinosa 50g, Raw Astragalus membranaceus 50g, Stir-fried Atractylodes macrocephala 10g, Stir-fried Citrus aurantii 10g, Poria cocos 10g, psoralen 10g, amethyst 30g, salvia miltiorrhiza 15g. A total of twelve herbs.

[0016] Weigh the above twelve herbs in parts by weight, add 10 times of water and decoct three times (the first soaking time is 60 minutes), each time for 2 hours, filter, combine each filtrate, concentrate under reduced pressure to about 4000mL, straight tube high-speed Centrifuge in a centrifuge, combine the centrates, add water to 4500mL, stir evenly, subpackage, and sterilize with steam for 45 minutes to obtain its liquid preparation.

Embodiment 2

[0018] A compound combination medicine for treating cor pulmonale, comprising the following components in parts by weight: 20 parts of Codonopsis radix, 10 parts of Ophiopogon japonicus, 20 parts of Schisandra chinensis, 20 parts of Chinese yam, 30 parts of rehmannia glutinosa, 30 parts of raw astragalus, and 12 parts of fried Atractylodes macrocephala , 10 parts of fried Fructus Aurantii, 10 parts of Poria cocos, 10 parts of psoralen, 30 parts of amethyst, 12 parts of Danshen. A total of twelve herbs.

[0019] Weigh the above twelve herbs according to parts by weight, add 12 times of water to decoct twice (the first soaking time is 60 minutes), each time for 2 hours, filter, combine the filtrates, and concentrate under reduced pressure to a relative density of 1.10 (60°C test) extract, add ethanol until the alcohol content is 60%, let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell and continue to concentrate to a relative densit...

Embodiment 3

[0021] 15 parts of Codonopsis, 10 parts of Ophiopogon japonicus, 15 parts of Schisandra chinensis, 15 parts of Chinese yam, 25 parts of rehmannia glutinosa, 25 parts of raw astragalus, 12 parts of fried Atractylodes macrocephala, 10 parts of fried Citrus aurantium, 10 parts of Poria cocos, 10 parts of psoraleae, 20 parts of amethyst 12 parts of Danshen. A total of twelve herbs.

[0022] Weigh the above twelve herbs according to parts by weight, add 15 times the amount of water to soak for 45 minutes, decoct twice for 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a dipping solution with a relative density of 1.12 (measured at 60°C). Paste, add ethanol until the alcohol content is 65%, let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell, continue to concentrate to a relative density of about 1.30 (measured at 60°C), vacuum dry, crush, and pack into capsules, that is, Get caps...

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PUM

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Abstract

The invention discloses a compound medicine for treating cor pulmonale and its preparation method and application. The compound medicine is composed of the following components in parts by weight: Codonopsis 15-120 parts, Ophiopogon japonicus 10-50 parts, Schisandra chinensis 20-120 parts, 20-150 parts of Chinese yam, 20-150 parts of rehmannia glutinosa, 20-150 parts of raw Astragalus membranaceus, 10-90 parts of fried Atractylodes macrocephala, 10-90 parts of fried Citrus aurantium, 10-90 parts of Poria cocos, 10-100 parts of psoralen 60 parts, amethyst 30-100 parts, and salvia miltiorrhiza 10-120 parts. The compound medicine for treating cor pulmonale and its preparation method and application of the invention have the characteristics of good curative effect, no side effect and the like. The preparation method of the compound combination medicine for treating cor pulmonale is simple, fast, efficient and easy to operate. The prepared mixtures, tablets, capsules, pellets and the like are easy to carry and take.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a compound medicine for treating cor pulmonale and its preparation method and application. Background technique [0002] Chronic cor pulmonale is caused by chronic lesions in the lung tissue, pulmonary vessels or thorax, resulting in abnormal structure and (or) function of the lung tissue, resulting in increased pulmonary vascular resistance, increased pulmonary artery pressure, dilation or (and) hypertrophy of the right ventricle, accompanied by Or heart disease without right heart failure, and those caused by congenital heart disease and left heart disease should be excluded. The occurrence of pulmonary hypertension is the central link and prerequisite for the pathogenesis of chronic pulmonary heart disease, and hypoxia is an important mechanism for the formation of pulmonary hypertension. Inflammation and thrombosis result either ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P11/00A61P9/00A61K33/14
Inventor 史锁芳刘志辉
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM