TOF-PET image reconstruction method based on compressed sensing theory

A TOF-PET, compressed sensing technology, applied in the field of nuclear medicine imaging, can solve the problem of limited noise improvement, achieve the effect of noise suppression, improve image signal-to-noise ratio, and reduce drug dose

Active Publication Date: 2014-10-01
INST OF HIGH ENERGY PHYSICS CHINESE ACADEMY OF SCI
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Problems solved by technology

[0009] However, there is still room for improvement in the above methods
For example, although the TOF-PET in the prio

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  • TOF-PET image reconstruction method based on compressed sensing theory
  • TOF-PET image reconstruction method based on compressed sensing theory
  • TOF-PET image reconstruction method based on compressed sensing theory

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[0047]Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and thus their detailed descriptions will be omitted.

[0048] Furthermore, the described features, structures, or characteristics may be combined in any suitable manner in one or more example embodiments. In the following description, numerous specific details are provided in order to give a thorough understanding of example embodiments of the present disclosure. However, those skilled in the art will appreciate that the technical solutions of the present disclosure may be practic...

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Abstract

The invention provides a TOF-PET image reconstruction method based on the compressed sensing theory. The method includes the steps that firstly, according to the flight time positioning imaging principle, a first image is reconstructed based on a data set obtained through a TOF-PET detector and an initial image through a TOF reconstruction algorithm; secondly, according to the compressed sensing theory, a sparse representation of the first image is solved with lp norm minimality as the purpose, the first image is updated according to the solution result, and then a second image is obtained; thirdly, whether a stop condition is met or not is judged, if yes, the second image is a final image, if not, the initial image is updated to be the second image, and the first step is executed again. By means of the TOF-PET image reconstruction method, given time information can be completely utilized, acquisition time is shortened, and the drug dose is reduced; meanwhile, the image signal to noise ratio can be increased, noise can be remarkably suppressed, and therefore better image quality can be acquired.

Description

technical field [0001] The present disclosure relates to the technical field of nuclear medicine imaging, in particular to a TOF-PET image reconstruction method based on compressed sensing theory. Background technique [0002] Positron Emission Tomography (PET) is a non-invasive nuclear medicine imaging diagnosis technology widely used clinically. It provides functional information such as metabolism of the living body by imaging the radioactive tracer injected into the living body. It plays an important role in diagnosis, efficacy evaluation, basic medical research and new drug development. The main principle is: inject the radioactive tracer drug marked with positron nuclide into the subject, the positron nuclide decays and emits positrons, which annihilate with the negative electrons in the subject, resulting in two directions Instead, gamma photons, each with an energy of 511KeV, are thus detected by a strip of scintillation crystals placed around the object being inspe...

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Application Information

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IPC IPC(8): G06T5/50
Inventor 魏龙周小林贠明凯曹学香刘双全孙翠丽高娟李默涵魏存峰
Owner INST OF HIGH ENERGY PHYSICS CHINESE ACADEMY OF SCI
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