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Application of raspberry extract in preparation of drug for treating perimenopausal syndrome

A perimenopausal and raspberry technology is applied in the application field of raspberry extract in the preparation of medicines for treating perimenopausal syndrome, and achieves the effects of improving thymus glands, abundant raw materials and simple preparation method.

Inactive Publication Date: 2014-10-08
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although there are many studies on raspberry, there is no public report about the application of raspberry extract in the preparation of medicines for treating perimenopausal syndrome.

Method used

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  • Application of raspberry extract in preparation of drug for treating perimenopausal syndrome
  • Application of raspberry extract in preparation of drug for treating perimenopausal syndrome
  • Application of raspberry extract in preparation of drug for treating perimenopausal syndrome

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Embodiment Construction

[0008] The specific implementation of the present invention will be described in detail below in combination with specific situations.

[0009] In the specific implementation of the present invention, the application of raspberry extract in the preparation of medicines for the treatment of perimenopausal syndrome, the raspberry extract is to pulverize raspberry into a coarse powder passing through a 20-30 mesh sieve, and first add 10 times Raspberry weight petroleum ether reflux extraction 1h, degreasing, discarding petroleum ether; raspberry dregs volatilize petroleum ether, add 10 times the volume concentration of raspberry weight and soak in ethanol with a volume concentration of 80% for 0.5h, reflux extraction 2 times, each Once for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure until there is no alcohol smell, add distilled water to disperse until the amount of crude drug is equivalent to 0.3g / ml, to obtain a dispersion, and put the AB-8 macr...

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Abstract

The invention relates to an application of raspberry extract in preparation of a drug for treating perimenopausal syndrome. The raspberry extract is used for effectively solving the drug problem of treating the perimenopausal syndrome. A preparation method of the raspberry extract comprises the following steps: crushing raspberry into coarse powder, carrying out reflux extraction and degreasing by using petroleum ether and discarding the petroleum ether; volatilizing the petroleum ether in the raspberry residue, soaking by using ethyl alcohol, carrying out reflux extraction, filtering, recovering the ethyl alcohol from the filtrate under reduced pressure, adding distilled water to disperse, carrying out adsorption on a dispersion liquid by using macroporous adsorption resin, eluting by using distilled water firstly and discarding the water eluent; eluting by using ethyl alcohol and discarding the eluent; eluting by using ethyl alcohol again, recovering the ethyl alcohol from the ethyl alcohol eluent under reduced pressure till no alcohol smell, carrying out freeze drying and crushing. The raspberry extract has the effects of remarkably increasing thymus, spleen and uterus indexes and is effectively used for preparing the drug for treating the perimenopausal syndrome; and the application of the raspberry extract in preparation of the drug for treating the perimenopausal syndrome is realized.

Description

technical field [0001] The invention relates to medicine, in particular to the application of raspberry extract in the preparation of medicine for treating perimenopausal syndrome. Background technique [0002] Perimenopausal syndrome, also known as menopausal syndrome (MPS), refers to a series of syndromes mainly caused by autonomic nervous system dysfunction and accompanied by neuropsychological symptoms caused by the fluctuation or decrease of sex hormones in women before and after menopause. Menopause can be divided into natural menopause and artificial menopause. Natural menopause means that the follicles in the ovary are exhausted, or the remaining follicles lose their response to gonadotropins, and the follicles no longer develop and secrete estrogen, and cannot stimulate the growth of the endometrium, leading to menopause. [0003] Raspberry (scientific name: Rubus idaeus), also known as raspberry, japonica, raspberry, wheat bubble (resulting in the wheat harvest se...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P15/12
Inventor 苗明三冯素香刘奇
Owner HENAN UNIV OF CHINESE MEDICINE
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