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Compound folium callicarpae pedunculalae nose drops and preparation method thereof

The technology of a kind of herbal nasal drops and Zizhucao, which is applied in the field of compound Zizhucao nose drops and its preparation, can solve the problems of unsatisfactory curative effect and slow treatment effect, and achieve easy-to-obtain drug sources, low cost and lighten the burden Effect

Active Publication Date: 2014-10-29
江西乐成生物医疗有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are indeed many drugs for the treatment of epistaxis, but it can be seen from the clinical practice that the therapeutic effect is slow and the curative effect is not ideal.
And most of the existing medicines are oral medicines, which can only reach the bleeding wound in the nasal cavity from the blood at a very low concentration, and do not pose a threat to the stubborn germs at the wound, and some germs adhere to the nasal cavity On the nasal hair or mucous membrane layer, the drug in the blood cannot reach and destroy them at all

Method used

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  • Compound folium callicarpae pedunculalae nose drops and preparation method thereof
  • Compound folium callicarpae pedunculalae nose drops and preparation method thereof
  • Compound folium callicarpae pedunculalae nose drops and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 The preparation steps of compound purple pearl grass nasal drops are as follows:

[0029] (1) Take the coarse powder of Zizhucao, extract it twice with water, boil for 1 hour each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on the distribution funnel, discard the ethanol Mother liquor, precipitation, and drying below 60°C to obtain dry powder of crude water extract;

[0030](2) Put the burdock fruit and dandelion in a casserole respectively, add water and boil twice, boil for 1-2 hours for the first time, and boil for 0.5-1 hour for the second time, combine the two filtrates, concentrate, and dry to obtain Burdock fruit aqueous extract and dandelion aqueous extract;

[0031] (3) Take the result of step (1) and step (2), put it in a glass container, add distilled water to dissolve it, treat it once with activated carbon, filter it with suction, and control the compound Zizhucao nasal drops obtained, e...

Embodiment 2

[0033] Example 2 The preparation steps of compound purple pearl grass nasal drops are as follows:

[0034] (1) Take the coarse powder of Zizhucao, extract it twice with water, boil for 1 hour each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on the distribution funnel, discard the ethanol Mother liquor, precipitation, and drying below 60°C to obtain dry powder of crude water extract;

[0035] (2) Put the burdock fruit and dandelion in a casserole respectively, add water and boil twice, boil for 1-2 hours for the first time, and boil for 0.5-1 hour for the second time, combine the two filtrates, concentrate, and dry to obtain Burdock fruit aqueous extract and dandelion aqueous extract;

[0036] (3) Take the result of step (1) and step (2), put it in a glass container, add distilled water to dissolve it, treat it once with activated carbon, filter it with suction, and control the compound Zizhucao nasal drops obtained, ...

Embodiment 3

[0040] Example 3 The preparation steps of compound purple pearl grass nasal drops are as follows:

[0041] (1) Take the coarse powder of Zizhucao, extract it twice with water, boil for 1 hour each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on the distribution funnel, discard the ethanol Mother liquor, precipitation, and drying below 60°C to obtain dry powder of crude water extract;

[0042] (2) Put the burdock fruit and dandelion in a casserole respectively, add water and boil twice, boil for 1-2 hours for the first time, and boil for 0.5-1 hour for the second time, combine the two filtrates, concentrate, and dry to obtain Burdock fruit aqueous extract and dandelion aqueous extract;

[0043] (3) Take the result of step (1) and step (2), put it in a glass container, add distilled water to dissolve it, treat it once with activated carbon, filter it with suction, and control the compound Zizhucao nasal drops obtained, ...

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Abstract

The invention discloses compound folium callicarpae pedunculalae nose drops. Every 100ml of compound folium callicarpa pedunculate nose drops comprises the following main components: 10-15g of folium callicarpae pedunculalae water extract, 5-8g of burdock water extract and 3-6g of dandelion water extract. The compound folium callicarpae pedunculalae nose drops have the effects of clearing away heat and toxic materials, stopping bleeding and reducing blood, returning and cooling blood, purging intense heat and eliminating dampness, fixing muscles and securing the exterior, regulating qi and blood and nourishing yin and clearing internal heat, can perform high-concentration antibiotic and drug attack on persistent germs from the mucous membrane layer of the nasal cavity and the vibrissa and is obvious in curative effect of treating nasal hemorrhage and reliable in effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a compound Zizhucao nasal drop and a preparation method thereof. Background technique [0002] Epistaxis, also known as epistaxis, is one of the common clinical symptoms. It is mostly caused by nasal lesions, and can also be caused by systemic diseases. Occasionally, bleeding from adjacent lesions in the nasal cavity will flow out through the nasal cavity. Bleeding can occur in any part of the nasal cavity, and is most common in the anterior and inferior areas of the nasal septum. Sometimes jet or pulsatile arteriolar bleeding can be seen. Nosebleeds are mostly unilateral, but can also be bilateral; intermittent and repeated bleeding can also be continuous; the amount of bleeding varies, in mild cases, there is only blood in the nose, and in severe cases, it can cause hemorrhagic shock; repeated bleeding can cause Anemia, most bleeding can be stopped by itself. Epist...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P11/02A61P7/04A61P31/04
Inventor 陈林旭
Owner 江西乐成生物医疗有限公司
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