Supercharge Your Innovation With Domain-Expert AI Agents!

A pharmaceutical composition for treating organ fibrosis, its preparation method and application

An organ fibrosis and composition technology, which is applied in the field of pharmaceutical compositions for treating organ fibrosis, can solve the problems of lack of satisfactory western medicine prevention and treatment methods and the like

Inactive Publication Date: 2017-04-12
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although pulmonary fibrosis is reversible in treatment, there is still a lack of satisfactory prevention and treatment methods of western medicine, which may be related to the multiple factors of pulmonary fibrosis, multiple targets of disease, and the diversity of pathological processes.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A pharmaceutical composition for treating organ fibrosis, its preparation method and application
  • A pharmaceutical composition for treating organ fibrosis, its preparation method and application
  • A pharmaceutical composition for treating organ fibrosis, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 Preparation of the pharmaceutical composition of the present invention

[0027] Take 10 grams of Sunburned Ephedra, 10 grams of Almond, 18 grams of Zhuru, 12 grams of Scutellaria, 12 grams of Morus alba, 8 grams of Ginseng, 18 grams of Sunburned Astragalus, 18 grams of Salvia, 12 grams of Angelica, 3 grams of Saffron, and 8 grams of Chuanxiong. 18 grams of Radix Ophiopogon japonicus, 18 grams of Radix Asparagus, 18 grams of Radix Ginseng, and 5 grams of Radix Glycyrrhizae. Weigh each medicinal herb according to its quantity, mix it with sufficient amount of clean water, decoct with strong fire, then change to simmer for 10 to 15 minutes, collect the decoction, add water for decoction twice, and combine the decoctions each time, Instant soup.

Embodiment 2

[0028] Embodiment 2 Preparation of the pharmaceutical composition of the present invention

[0029] Take 13 grams of Sunburned Ephedra, 13 grams of Almond, 15 grams of Zhuru, 10 grams of Scutellaria, 10 grams of Morus alba, 6 grams of Ginseng, 15 grams of Sunburned Astragalus, 15 grams of Salvia, 10 grams of Angelica, 2 grams of Saffron, and 6 grams of Chuanxiong. gram, 15 grams of Ophiopogon japonicus, 15 grams of Radix Asparagus, 15 grams of Radix Ginseng, 4 grams of Radix Glycyrrhizae. After extracting twice with 70% v / v ethanol, the ethanol extract was combined, and the dregs were decocted twice with water, and the decoction was combined. Concentrate the ethanol extract and water decoction respectively, mix them, add appropriate amount of dextrin and soluble starch, and granulate to obtain granules.

Embodiment 3

[0030] Embodiment 3 Preparation of the pharmaceutical composition of the present invention

[0031]Take 7 grams of ephedra, 7 grams of almonds, 20 grams of Zhuru, 15 grams of skullcap, 15 grams of Morus alba, 10 grams of ginseng, 20 grams of sunburned astragalus, 20 grams of salvia, 15 grams of angelica, 4 grams of saffron, and 10 grams of chuanxiong. gram, 20 grams of Ophiopogon japonicus, 20 grams of Radix Asparagus, 20 grams of Radix Ginseng, 6 grams of Radix Glycyrrhizae. Weigh each herbal flavor according to the amount, grind ginseng into very fine powder, mix with enough clean water, decoct the rest of the medicines with strong fire until boiling, then change the fire to simmer, and fry for about 10 minutes to 15 minutes, then collect the water Add ginseng powder to the decoction, mix well; decoct the dregs with water twice, add powder as before, combine the filtrate, concentrate and dry, add appropriate amount of microcrystalline cellulose, mix well, pack into capsules,...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a pharmaceutical composition for treating organ fibrosis. The pharmaceutical composition is an agent prepared from the following raw material medicines in parts by weight: 7-13 parts of ephedra, 7-13 parts of almond, 15-20 parts of caulis bambusae in taeniam, 10-15 parts of scutellaria baicalensis, 10-15 parts of the root bark of white mulberry, 6-10 parts of ginseng, 15-20 parts of astragalus, 15-20 parts of the root of red-rooted salvia, 10-15 parts of Chinese angelica, 2-4 parts of crocus sativus, 6-10 parts of ligusticum wallichii, 15-20 parts of radix ophiopogonis, 15-20 parts of asparagus fern, 15-20 parts of the root of straight ladybell and 4-6 parts of liquorice. The invention also provides a preparation method and application of the pharmaceutical composition. According to monarch, ministerial and adjuvant drugs, the various medicines are clear in functions and supplement with one another, the essence of embattled speculative scientific research methodology in a compound compatibility medicine unique in traditional Chinese medicine is fully exerted, the effects of stopping asthma, dredging collaterals and strengthening healthy energy can be achieved, the composition has a good treatment effect on'excessive superficial and deficient root' special syndrome types of pulmonary fibrosis in the formula, and a novel choice is provided for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating organ fibrosis, a preparation method and application thereof. Background technique [0002] Pulmonary fibrosis (Pulmonary fibrosis / PF) is a disease caused by various causes of lung inflammation, continuous alveolar damage and repeated destruction, repair, reconstruction and excessive deposition of extracellular matrix (Extracellular matrix / ECM), resulting in normal lung tissue structure A disease spectrum characterized by changes and loss of function, which is the common outcome of chronic lung diseases caused by a variety of causes, and is the main pathological basis of respiratory failure. Its etiology and pathogenesis are complex. The regulation of various cytokines and their networks is an extremely important factor in the pathological mechanism of its occurrence and development. [0003] Pulmonary fibrosis belongs to a class of refractory and serious diseases that have attracted a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P43/00A61P11/00
Inventor 李戎彭彩钰程琳赵荣光
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More