A traditional Chinese medicine tablet for treating diabetic retinopathy and its application

A technology of traditional Chinese medicine tablets and medicinal residues, which is applied in the directions of medical preparations with non-active ingredients, medical preparations containing active ingredients, and pill delivery, etc. ingredients, etc.

Active Publication Date: 2016-08-24
BEIJING HANDIAN PHARMA CO LTD +1
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The above method is only a simple preparation method of traditional Chinese medicine decoction, and does not consider how to fully extract the active ingredients in the medicine, which causes a serious waste of medicinal material resources, but the medicinal effect is not significant; at the same time, the water decoction brings a large dosage and poor taste , inconvenient to carry, not suitable for long-term storage

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A traditional Chinese medicine tablet for treating diabetic retinopathy and its application
  • A traditional Chinese medicine tablet for treating diabetic retinopathy and its application
  • A traditional Chinese medicine tablet for treating diabetic retinopathy and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Example 1 a Chinese medicine tablet

[0076] API prescription:

[0077] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0078] The concrete steps of described preparation method are as follows:

[0079] (1) Prepare various medicinal materials according to the prescription.

[0080] (2) Take cinnamon, add water 10 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for subsequent use; add 2 times the volume of absolute ethanol to dissolve the volatile oil; take 10 times the weight of the volatile oil volume of β-cyclodextrin, add water 25 times the weight of β-cyclodextrin to make β-cyclodextrin aqueous solution; at a speed of 150 rpm, slowly add volatile oil ethanol to the β-cyclodextrin aqueous solution After the addition of the solution, continue to stir for 1.5 hours, refrigera...

Embodiment 2

[0087] Example 2 a Chinese medicine tablet

[0088] API prescription:

[0089] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0090] The concrete steps of described preparation method are as follows:

[0091] (1) Prepare various medicinal materials according to the prescription.

[0092] (2) Take cinnamon, add water 8 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 1 volume of absolute ethanol to dissolve the volatile oil, and take 6 times the volume of the volatile oil β-cyclodextrin, β-cyclodextrin aqueous solution made by adding water 15 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous solution After the addition, continue to stir for 1.5 hours, refrigerate for 12 hours, filter, an...

Embodiment 3

[0099] Example 3 a Chinese medicine tablet

[0100] API prescription:

[0101] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0102] The concrete steps of described preparation method are as follows:

[0103] (1) Prepare various medicinal materials according to the prescription.

[0104] (2) Take cinnamon, add water 12 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 3 times the volume of absolute ethanol to dissolve the volatile oil, and take 20 times the volume of the volatile oil β-cyclodextrin, β-cyclodextrin aqueous solution made by adding water 40 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous solution After the addition, continue to stir for 1.5 hours, refrigerate for 12 hours...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention provides a traditional Chinese medicine tablet for treating diabetic retinopathy and its application, and provides a traditional Chinese medicine tablet. The raw materials of the traditional Chinese medicine tablet are composed of 30-60 parts by weight of Radix Astragali, 9-15 parts by weight of Ligustrum lucidum, 9-30 parts by weight of motherwort, 3-10 parts by weight of black plum, 2-9 parts by weight of coptis, 1-5 parts by weight of cinnamon, 3-9 parts by weight of Budisma; prepared by the following method: extract volatile oil from cinnamon, and use β- Cyclodextrin inclusion; cinnamon dregs, astragalus, Ligustrum lucidum, Mimenghua, and black plum are first extracted with ethanol solution I, and then refined with macroporous adsorption resin to obtain dry extract powder 1; Coptis chinensis and motherwort are first extracted with ethanol solution III extraction, and then refined by ion exchange resin, to obtain dry extract powder 2; dry extract powder 1, dry extract powder 2 and volatile oil inclusion compound, adding pharmaceutically acceptable excipients, and pressing into tablets to obtain the traditional Chinese medicine tablet. Compared with the prior art, the tablet of the invention has higher active substance content in the unit preparation and better pharmacological effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine tablet for diabetic retinopathy and its application. Background technique [0002] Diabetic Retinopathy (DR) is one of the serious and common eye complications of diabetes. With the prolongation of the duration of diabetes, the incidence of DR also increased. The incidence of diabetic retinopathy is about 50% in those with a course of more than 8 years. The early symptoms of the disease are not obvious and are easy to be ignored. In the late stage, there is no effective control method, and the disease is lingering and intractable. If the disease is not treated, the consequences are serious, and it is the main cause of adult blindness, with a blinding rate of 8-12%, which has a serious adverse effect on the quality of life of the affected population. Therefore, the prevention and treatment of DR has become a major research ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61K9/20A61K47/48A61P3/10A61P9/10
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap