Medicine for intervening before anesthesia and preparation method thereof

A technology of drugs and antler gum, applied in drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as extremely passive work of anesthesiologists, no other preventive measures for deconstruction disorders, and no clear correlation between arrhythmia categories.

Inactive Publication Date: 2014-12-03
冯念海
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The causes of arrhythmia during anesthesia are related to factors such as electrolyte disturbance, anesthesia medication, surgery, and anesthesia operations. However, the occurrence of arrhythmia is diverse, and frequency increase, frequency decrease, ectopic pacing, and conduction block all occur during anesthesia. There is no clear correlation between the type of arrhythmia and surgery and anesthesia. As a result, currently, arrhythmia during anesthesia is only treated symptomatically, that is, corresponding interventions are performed according to the type of symptoms after occurrence during anesthesia. In addition to correcting electrolyte imbalance before surgery and Without other preventive measures, the work of anesthesiologists is extremely passive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1, the weight ratio of raw materials: 20g of alpinia, 10g of safflower parasite, 6g of piercing stone, 10g of reed stem, 16g of golden buckwheat stem and leaf, 10g of motherwort, 10g of coix seed, 10g of kudzu root, 10g of honeysuckle, 2g of Jiulixiang , antler glue 16g, scallion 20g.

[0035] The preparation method of Example 1 is: mix alpine ginger, safflower parasitic, piercing stone, reed stem, golden buckwheat stem and leaf, motherwort, coix seed, kudzu root, honeysuckle, mulberry, antler gum, scallion white, add water and decoct, 30 After 2 minutes, take the filtrate, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide it into two parts and take it in the morning and evening.

Embodiment 2

[0036] Example 2, the weight ratio of raw materials: 10 parts of alpinia, 6 parts of safflower, 3 parts of piercing stone, 6 parts of reed stems, 15 parts of golden buckwheat stems and leaves, 6 parts of motherwort, 6 parts of coix seed, and 6 parts of kudzu root 1 part, 6 parts of honeysuckle, 1 part of Jiulixiang, 15 parts of antler gum, and 10 parts of scallion.

[0037] Prepared as follows:

[0038] (1) Boil the scallion white for 0.5 hours, filter the boiling liquid, add crushed antler gum powder to the cooking liquid, heat at 80°C until the antler gum is completely melted, concentrate to a relative density of 1.2, drop into cold water drop by drop to cool under heat , take out and dry in the shade to become rubber beads for later use;

[0039](2) Grind Jiulixiang and golden buckwheat stems and leaves into powder, pass through a 20-mesh sieve, mix, and extract with supercritical carbon dioxide circulation countercurrent for 1 hour, the extraction pressure is 5Mpa, and th...

Embodiment 3

[0042] Example 3, the weight ratio of raw materials: 20 parts of alpinia, 10 parts of safflower, 6 parts of piercing stone, 10 parts of reed stem, 16 parts of golden buckwheat stem and leaf, 10 parts of motherwort, 10 parts of coix seed, 10 parts of kudzu root 10 parts of honeysuckle, 2 parts of Jiulixiang, 16 parts of antler gum, 20 parts of scallion.

[0043] Prepared as follows:

[0044] (1) Boil the scallion white for 1 hour, filter the cooking liquid, add crushed antler gum powder to the cooking liquid, heat at 90°C until the antler gum is completely melted, concentrate to a relative density of 1.3, and drop into cold water drop by drop to cool under heat , take out and dry in the shade to become rubber beads for later use;

[0045] (2) Grind Jiulixiang and golden buckwheat stems and leaves into powder, pass through a 20-mesh sieve, mix, and extract with supercritical carbon dioxide circulation countercurrent for 4 hours, the extraction pressure is 20Mpa, and the extract...

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PUM

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Abstract

The invention discloses a medicine for intervening before anesthesia and a preparation method thereof, aiming at solving the problem of intervening arrhythmia during anesthesia. The preparation method is characterized by comprising the following steps: (1) adding grinded antler gum coarse powder into fistular onion stalk boiling liquid, heating until the antler gum is completely molten, concentrating, dripping cold water, and drying in shade to obtain a glue bead for later use; (2) extracting Murraya exotica and stems and leaves of fagopyrum dibotrys to obtain mixed volatile oil; (3) decocting and filtering alpinia japonica, radix cudramiae, rhizoma phragmitis, herba leonuri, lonicera japonica, kudzu vine root, semen coicis and scurrula parasitica, concentrating, heating and stirring, adding the glue bead obtained in the step (1), grinding to dissolve the glue bead, adding the mixed volatile oil obtain in the step (2) under a cooling and stirring condition, and uniformly mixing to obtain a primary material; (4) drying and grinding the primary material obtained in the step (3) to obtain active particles. Clinical experiments prove that the medicine has the characteristics of good curative effect and relatively high safety when being used for preventing arrhythmia during anesthesia, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pre-anesthesia intervention drug and a preparation method thereof. Background technique [0002] Arrhythmia is an abnormality in the frequency, rhythm, origin, conduction velocity, or sequence of cardiac impulses. Sinus arrhythmias include sinus tachycardia, sinus bradycardia, sinus arrhythmia, and sinus arrest. Ectopic rhythm includes escape rhythm, premature systole, paroxysmal tachycardia, atrial flutter, atrial fibrillation, ventricular flutter, and ventricular fibrillation. Impulse to abnormal arrhythmias include sinoatrial block, intraatrial block, atrioventricular block, left or right bundle branch block, intraventricular block, pre-excitation syndrome. [0003] During anesthesia, the incidence of arrhythmia in cardiac and non-cardiac operations is very high. According to literature reports, even if patients with a history of arrhythmia have not had an attac...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P9/06A61K35/32
Inventor 冯念海唐俊霞郑升法
Owner 冯念海
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