Microfluidics droplet detection system and method based on capacitive sensor

A capacitive sensor and detection system technology, applied in the direction of material capacitance, instruments, measuring devices, etc., can solve the problems of changes in the biochemical activity of analytical substances, inability to accurately control droplets, unfavorable integration, etc.

Inactive Publication Date: 2015-01-07
TIANJIN UNIVERSITY OF TECHNOLOGY
View PDF6 Cites 26 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, fluorescent labeling may cause changes in the biochemical activity of the analyte and affect the reliability of the results.
The photomultiplier tube detects the average informa

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Microfluidics droplet detection system and method based on capacitive sensor
  • Microfluidics droplet detection system and method based on capacitive sensor
  • Microfluidics droplet detection system and method based on capacitive sensor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0051] Embodiment: A microfluidic droplet detection system based on a capacitive sensor, characterized in that it includes a droplet microfluidic chip, a DC voltage stabilization circuit unit, a signal detection circuit unit, and a computer; wherein the droplet microfluidic The control chip is a chip structure that integrates the capacitive sensor and the microchannel that produces the micro-droplet; figure 1 ); the lower sheet is a microchannel sheet, welded with sample I inlet, sample II inlet 3, droplet outlet 4, intersection 6, electrode terminal, sample I channel, sample II channel 11 and droplet generation channel 12 The sample I inlet is connected to the sample I channel; the sample II inlet 3 is connected to the sample II channel 11; the sample I channel and the sample II channel 11 are connected to the droplet generation channel 12 through the intersection 6; The droplet generating channel 12 is connected to the droplet outlet 4; the capacitive sensor 5 is placed abo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A microfluidics droplet detection system based on a capacitive sensor is characterized by comprising a droplet microfluidics chip, a direct-current voltage stabilizing circuit unit, a signal detection circuit unit and a computer, and the droplet microfluidics chip is of a structure according to which the capacitive sensor is integrated with a microchannel used for generating micro-droplets. A droplet detection method comprises the steps of sample pumping, droplet formation and droplet detection. The system and method have the advantages that the structure is simple, detection is conducted by means of the change of the capacitance, detection is quick, the size of the system is small, integration can be realized, the system and method are suitable for analysis of expensive samples and reagents, and manufacturing and implementation are easy.

Description

(1) Technical field: [0001] The invention belongs to the field of microfluidic chip analysis, in particular to a capacitive sensor-based microfluidic droplet detection system and detection method. (two) background technology: [0002] The microfluidic chip integrates the basic operation units involved in the fields of biology and chemistry, such as sample preparation, reaction, separation, detection, cell culture, sorting, and lysis, on a chip of several square centimeters. A network of microchannels is formed to run through the entire system with controllable fluids to replace various functions of conventional chemical or biological laboratories. The biggest advantage of microfluidic chips is the flexible combination and large-scale integration of various unit technologies on an overall controllable micro platform, which makes microfluidic chips likely to become an important platform for the development of biochemical analysis technology in the future. Droplet microfluidic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G01D21/02G01N27/22
Inventor 魏巍吴方郭书祥
Owner TIANJIN UNIVERSITY OF TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap