Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Operation rinsing water solution as well as preparation method and application thereof

A technology for flushing aqueous solutions and aqueous solutions, which can be used in pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc., and can solve problems such as poor stability and toxic and side effects.

Inactive Publication Date: 2015-01-21
ZHEJIANG TIANRUI PHARMA
View PDF14 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0021] As mentioned above, a large number of rinsing solutions are disclosed in the prior art, but these rinsing solutions still have certain defects.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Operation rinsing water solution as well as preparation method and application thereof
  • Operation rinsing water solution as well as preparation method and application thereof
  • Operation rinsing water solution as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] (1) Use an electronic balance to accurately weigh 95mmol sodium chloride, 1.5mmol sodium gluconate, 10mmol sodium acetate, 0.4mmol potassium chloride, 2.3mmol magnesium chloride, 0.5mmol L-lysine, 2.5mmol sodium tartrate, 0.6mmol citrate Sodium citrate, 4.5mmol glycerol, 26.7mmol sodium bicarbonate and 3.6mmol potassium bicarbonate;

[0072] (2) Add the above-mentioned weighed sodium chloride, sodium gluconate, sodium acetate, sodium tartrate, sodium citrate and sodium bicarbonate to water for injection, fully stir and dissolve to obtain the first dosing; wherein the amount of water for injection such that Na + Concentration 420mmol / L;

[0073] (3) Add the above-mentioned weighed potassium chloride, magnesium chloride, L-lysine, glycerol and potassium bicarbonate to the first dosing, fully stir and dissolve, then add water for injection to obtain the second dosing; The amount of water used is such that Na + Concentration 210mmol / L;

[0074] (4) Add activated carbon ...

Embodiment 2

[0078] (1) Use an electronic balance to accurately weigh 100mmol sodium chloride, 2.5mmol sodium gluconate, 15mmol sodium acetate, 0.607mmol potassium chloride, 3.4mmol magnesium chloride, 1mmol L-lysine, 3mmol sodium tartrate, 0.8mmol citric acid Sodium, 5mmol glycerol, 19.1mmol sodium bicarbonate and 3.893mmol potassium bicarbonate;

[0079] (2) Add the above-mentioned weighed sodium chloride, sodium gluconate, sodium acetate, sodium tartrate, sodium citrate and sodium bicarbonate to water for injection, fully stir and dissolve to obtain the first dosing; wherein the amount of water for injection such that Na + Concentration 435mmol / L;

[0080] (3) Add the above-mentioned weighed potassium chloride, magnesium chloride, L-lysine, glycerol and potassium bicarbonate to the first dosing, fully stir and dissolve, then add water for injection to obtain the second dosing; The amount of water used is such that Na + Concentration 290mmol / L;

[0081] (4) Add activated carbon for n...

Embodiment 3

[0085] (1) Use an electronic balance to accurately weigh 94.5mmol sodium chloride, 3.5mmol sodium gluconate, 15mmol sodium acetate, 0.5mmol potassium chloride, 4.224mmol magnesium chloride, 1.5mmol L-lysine, 3.5mmol sodium tartrate, 1mmol citrate Sodium citrate, 5.5mmol glycerol, 27mmol sodium bicarbonate and 4mmol potassium bicarbonate;

[0086] (2) Add the above-mentioned weighed sodium chloride, sodium gluconate, sodium acetate, sodium tartrate, sodium citrate and sodium bicarbonate to water for injection, fully stir and dissolve to obtain the first dosing; wherein the amount of water for injection such that Na + Concentration 450mmol / L;

[0087] (3) Add the above-mentioned weighed potassium chloride, magnesium chloride, L-lysine, glycerol and potassium bicarbonate to the first dosing, fully stir and dissolve, then add water for injection to obtain the second dosing; The amount of water used is such that Na + Concentration 375mmol / L;

[0088] (4) Add activated carbon fo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an operation rinsing water solution as well as a preparation method and application thereof. The rinsing water solution is prepared from sodium chloride, sodium gluconate, sodium acetate, potassium chloride, magnesium chloride, L-lysine, sodium tartrate, sodium citrate, glycerol, sodium bicarbonate and potassium bicarbonate. The operation rinsing water solution of which the sodium ion concentration, potassium ion concentration, Na<+1> / Cl<-1>, osmotic pressure and pH value are in specific ranges is prepared by specifically selecting specific ingredients properly determining usage and regulating pH value, and when the conditions are met at the same time, the operation rinsing water solution is safe and non-toxic, has excellent stability, and has tremendous application value and industrial production potential in medical field and clinical application.

Description

technical field [0001] The invention relates to a liquid for surgery and its preparation method and application, more specifically to an aqueous solution for surgical flushing and its preparation method and application, and belongs to the field of liquid products for surgery. Background technique [0002] During surgery, in order to obtain a clearer view, it is often necessary to lavage and flush the organs or tissues during the operation. After the operation is completed, the operation area also needs to be rinsed to remove microorganisms such as residual blood and bacteria in the operation area. In addition, the irrigation fluid can also be used as a carrier for drugs such as antibiotics, thereby preventing infection and reducing postoperative complications. Relatively large volumes of irrigating fluids have been shown to enter the systemic circulation, therefore, these irrigating fluids must be considered as a systemic drug requiring a high level of safety and compatibil...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K33/14A61K47/02A61K47/04A61P31/04A61K31/047A61K33/06A61K33/00A61K31/198A61K31/194A61K31/191
CPCA61K33/14A61K9/08A61K31/047A61K31/19A61K31/191A61K31/194A61K31/198A61K33/00A61K33/06A61K2300/00
Inventor 崔友李伟王恒彩夏小秋高余芬
Owner ZHEJIANG TIANRUI PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com