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Antiviral new application of radix sanguisorbae or extract thereof

A technology of extracts and uses, applied in the field of preparation of antiviral drugs, to achieve good therapeutic effect, improve patient compliance, safety and non-toxic side effects

Active Publication Date: 2015-04-15
广西英路维特药物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, so far, there have been no relevant reports on the application of Burnet or its extracts to various viral skin diseases caused by papillomaviruses.

Method used

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  • Antiviral new application of radix sanguisorbae or extract thereof
  • Antiviral new application of radix sanguisorbae or extract thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] The preparation of the original medicine powder of embodiment 1 Burnet and the pill containing the original medicine powder of Burnet

[0050] Take 1000g of Burnet medicinal material, clean it, pulverize it into fine powder according to the conventional method, pass through a 100-mesh sieve, and mix well to obtain the original medicinal powder of Burnet. Take the original medicinal powder of Burnet, and use about 40g of refined honey for every 100g of powder, combine it, make pills, pack, and make pills.

[0051] [Usage and Dosage] Take orally. 2 to 3 times a day, 1 to 2 pills each time.

Embodiment 2

[0052] The preparation of embodiment 2 Burnet extract and the ointment containing this Burnet extract

[0053] Take Burnet elm and crush it into coarse powder, for example, pass through 40 meshes, take 1000g of Burnet elm coarse powder, decoct in water twice, 1.5h each time, add 10 times the amount of water for the first time, that is, 10L water, and 8 times for the second time amount, that is, 8L of water, combined the filtrates, concentrated under reduced pressure, and dried to obtain 375g of Burnet Burnet extract.

[0054] According to the ratio of raw and auxiliary materials shown in Table 1, the ointment was prepared by a conventional preparation method.

[0055] Table 1 contains the ratio of raw and auxiliary materials of the ointment of Burnet extract

[0056] material ingredient

weight percentage (%)

Burnet Burnet extract that embodiment 2 makes

15

vaseline

3

Isopropyl myristate

6

lanolin

5

Lecithin

...

Embodiment 3

[0059] Embodiment 3 Burnet extract and the preparation of the suppository containing the Burnet extract

[0060] Take the medicinal material of Burnet and crush it into a coarse powder, for example, pass through 40 meshes, take 1000g of the coarse powder of the medicinal material of Burnet, reflux extraction with 70% ethanol for 3 times, each time for 2 hours, the amount of solvent is 10 times for the first time, and 8 times for the second time, For the third time, 6 times the amount, the filtrate was combined, concentrated under reduced pressure, and the precipitate was removed. The supernatant was subjected to macroporous resin separation, and was first eluted with water until colorless, then eluted with 10% ethanol of 2 times the column volume, and finally washed with 2 60% ethanol was eluted with twice the column volume, and the 60% ethanol eluate was collected, concentrated to an appropriate amount through a membrane, and then spray-dried to obtain 284 g of Burnet burnet e...

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PUM

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Abstract

The invention provides a new application of radix sanguisorbae or an extract thereof in preparation of an anti-papillomavirus drug. The radix sanguisorbae and a preparation thereof provided by the invention are used in prevention or treatment of viral skin diseases, such as condyloma acuminatum, can obtain better therapeutic effect in shorter use time, is safe, has no toxic or side effect, and provides a new choice for clinical medication.

Description

technical field [0001] The present invention relates to the use of Burnet eucalyptus or its extract in preparing antiviral medicine. Background technique [0002] Viral skin diseases are caused by viral infections. When the virus invades the body, it has a strong affinity for nerve tissue and skin tissue. Those who are close to the nerves can cause herpes zoster, etc., and those who are close to the skin can form warts. Warts are benign growths caused by viruses. Common warts, flat warts, and genital warts are caused by human papillomavirus (HPV). Human papillomavirus (HPV) is a kind of papillomavacuolating virus A belonging to Papovaviridae. It is a spherical DNA virus that can cause squamous epithelial proliferation of human skin and mucous membranes. Symptoms such as common warts and genital warts (condyloma acuminatum). With the rapid increase in the incidence of genital warts among sexually transmitted diseases and the increase of cervical cancer and anal cancer, hu...

Claims

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Application Information

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IPC IPC(8): A61K36/739A61P17/12A61P31/20
CPCA61K9/0014A61K9/06A61K9/2068A61K36/739A61K47/44A61K2236/33A61K2236/331A61K2236/333
Inventor 苏柘僮熊永爱邹俊波
Owner 广西英路维特药物有限公司
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