Radioiodine-131 vapor trapping device

Abstract

The invention provides a radioiodine-131 vapor trapping device which comprises a cold trap, an overflow groove, an alkaline liquor bottle, a heater, a nitrogen bottle, a refrigerating fluid storage tank, a product bottle and a vacuum pump, wherein the cold trap is respectively connected to the overflow groove, the alkaline liquor bottle, the heater, the refrigerating fluid storage tank, the product bottle and the vacuum pump by virtue of pipelines; the alkaline liquor bottle, the heater and the refrigerating fluid storage tank are respectively connected to the nitrogen bottle; and the product bottle is connected to the vacuum pump. The device disclosed by the invention can be used for effectively trapping radioiodine-131 vapor and converting the radioiodine-131 vapor into a Na131I solution which can be more than 10Ci / mL in concentration, so that the device is more conducive to the production of radioactive drugs having high specific activity. The device disclosed by the invention is compact and smart, and is convenient to operate.

Description

technical field [0001] The invention belongs to the technical field of radioisotope preparation, and in particular relates to a radioactive iodine-131 vapor trapping device. Background technique [0002] Radiopharmaceuticals made of radioactive iodine-131 are widely used in clinical diagnosis and treatment of modern nuclear medicine. The main production method of radioactive iodine-131 raw materials is distillation extraction from reactor irradiated tellurium dioxide and extraction from 235 Extracted by distillation from the mixture of lobes of U. The above-mentioned production methods all distill radioactive iodine-131 by heating and absorb it with dilute lye (generally NaOH solution with a concentration less than 0.5mol / L) to obtain raw materials for the production of radiopharmaceuticals. At present, radioactive iodine-131 is mainly distilled and extracted from tellurium dioxide after reactor irradiation by dry distillation. [0003] Documents show that the present inve...

AI Technical Summary

Problems solved by technology

Activated TeO can be loaded due to existing radioactive iodine-131 distillation equipment 2 The amount is small, especially at reactor thermal neutron fluence rates below 1*10 14 n / cm 2 s, the output of radioactive iodine-131 is low, and the volume of alkali absorption liquid added by the existing iodine-131 vapor trapping device is often greater than 10mL, resulting in the final obtained Na 131 I solution product concentration is low

At present, no domestic scientific research institutions and production enterprises have used this radioactive iodine-131 capture device for high-concentration Na 131 The example report of I solution production, and in reality urgently needs a kind of production high concentration Na with compact structure, safe and convenient operation. 131 Radioactive iodine-131 vapor trapping device for I solution

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