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Preparation method of ultramicro spirulina powder as well as preparation and application thereof

A kind of spirulina powder and ultrafine technology, applied in the field of traditional Chinese medicine, can solve the problems of unreasonable formula, cumbersome production process, and many auxiliary materials

Inactive Publication Date: 2015-05-27
江苏海王健康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The spirulina products currently on the market are not high in purity, contain more auxiliary materials, the production process is cumbersome, and the cost is high
The present invention proposes a production process of spirulina tablets, a production process of spirulina capsules and a production process of spirulina soft capsules, so as to solve the unreasonable formula of existing spirulina products, low purity and cumbersome production process, The problem of low product quality, and speed up industrial production, improve productivity efficiency

Method used

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  • Preparation method of ultramicro spirulina powder as well as preparation and application thereof
  • Preparation method of ultramicro spirulina powder as well as preparation and application thereof
  • Preparation method of ultramicro spirulina powder as well as preparation and application thereof

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Experimental program
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Effect test

Embodiment 1

[0048] The preparation method of embodiment 1 ultrafine spirulina powder (average particle diameter is 200~800nm)

[0049] Get common spirulina (the spirulina that Sanya Haiwang Marine Biotechnology Co., Ltd. produces and provides, dry, pulverize, cross 100 mesh sieves), be processed into superfine spirulina powder (200~800nm), and its method comprises the following steps:

[0050] ① Coarse powder the dried spirulina powder (moisture content below 5%) to below 100 mesh.

[0051] ② The crushed spirulina powder is ultrafinely pulverized by a high-energy nano-impact mill, and the grinding medium in the high-energy nano-impact mill tank is continuously impacted and ground for 6-10 hours, so that the average particle size of the spirulina powder reaches 200-800nm .

[0052] See Table 1 for detailed production data

[0053] Table 1 Production dynamic data table of ultrafine spirulina powder

[0054] the batch

[0055] 3

[0056] (Remarks: These 3 batches have ...

Embodiment 2

[0057] The preparation method of embodiment 2 ultrafine spirulina powder (average particle diameter is 200~800nm)

[0058] ① Freeze-thaw extraction: take common spirulina (spirulina produced by Sanya Haiwang Marine Biotechnology Co., Ltd., dry, crush, and pass through a 100-mesh sieve) and soak it in distilled water (algae: water ratio 1:1, W / W) at room temperature Put it overnight, put it in the refrigerator to cool to -15°C the next day, then put it in a constant temperature and humidity box at 40°C to thaw quickly, repeat freezing and thawing 3 times, centrifuge separately to get the supernatant, and keep the separated algae residue for later use , combined, and freeze-dried (the main drying stage controls the temperature at -5°C, the vacuum chamber pressure is 15Pa, and the drying time is 380min) to obtain the water extract;

[0059] ②The algal residue is dried to obtain the algal residue product.

[0060] ③Uniformly mix the water extract and the algae residue product to ...

Embodiment 3

[0070] A: Preparation process 1 of spirulina sheet (the raw material is common spirulina powder)

[0071] 1) Formula 1: ordinary spirulina powder: 3930g; hypromellose: 16g; magnesium stearate: 64g.

[0072] ① Accurately weigh 3930g of ordinary spirulina powder (the spirulina produced by Sanya Haiwang Marine Biotechnology Co., Ltd., dried, crushed, and passed through a 100-mesh sieve).

[0073] ② Weigh 16g of hypromellose and purified water and mix them uniformly in proportion to prepare a 5.0% hypromellose solution as a binder;

[0074] ③Add the hypromellose solution into the spirulina powder, and pass through a 20-mesh sieve to obtain wet particles.

[0075] ④ The wet granules are dried at 50-60°C until the water content of the granules is less than 3.0%, to obtain dry granules.

[0076] ⑤Add 64g of magnesium stearate and mix for 20 minutes to obtain total blend granules.

[0077] ⑥Place the blended granules in a tablet press, and press the tablet with a tablet weight of 0...

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Abstract

The invention discloses a preparation process of ultramicro spirulina powder. The preparation process of the ultramicro spirulina powder comprises the following two steps: (1) directly superfine grinding the spirulina; and (2) uniformly mixing the spirulina water extract and the extracted spirulina residue product to obtain the spirulina powder. The average grain size of the spirulina powder is 200-800 nm. The prescription and the preparation process of the tablet, the capsule and the soft capsule of the ultramicro spirulina powder and the common spirulina powder (less than 100 meshes) are created and researched based on the ultramicro spirulina powder. The additive amount of the auxiliary materials is greatly reduced; by adopting the new preparation molding process, the problems of unreasonable prescription of the current spirulina product, many auxiliary materials, multiple varieties, low purity, tedious production process and low product quality can be solved; and the industrial production speed can be quickened and the production efficiency can be increased. The prepared product is detected. The function test proves that the ultramicro spirulina powder and the common spirulina powder have the radiation-proof effect and liver-protective effect.

Description

technical field [0001] The invention relates to a preparation method of ultrafine spirulina powder, its preparation and application, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Spirulina usually refers to two kinds of blue-green algae of the genus Arthrospira that are eaten by humans and animals——Arthrospira maxima (scientific name Arthrospira maxima) and Spirulina flat top (scientific name Arthrospira platensis). These two varieties were originally classified into the genus Spirulina (scientific name Spirulina), and later into the genus Arthrospira, but they are still customarily called "Spirulina". For thousands of years, the aborigines of Lake Chad in Africa and Lake Texcoco in Mexico have been eating spirulina as food. Countries all over the world have taken it as a nutritional supplement for 40 years, and no poisoning after overdose has been found. . Therefore, people generally believe that long-term use of spiruli...

Claims

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Application Information

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IPC IPC(8): A61K35/748A61K9/20A61K9/48A61P17/16A61P1/16A61P37/04A23L1/29A23L33/00
Inventor 严启新吕杰曾琪徐玮钟灵玉王巍程维茂宋廷久
Owner 江苏海王健康生物科技有限公司
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