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Antitumor drug and preparation method thereof

A technology of anti-tumor drugs and parts by weight, which is applied in the direction of anti-tumor drugs, drug combinations, pharmaceutical formulas, etc., and can solve the problems of different drugs and different drug effects, and achieve the effects of inhibiting growth, outstanding synergistic effect, and improving autoimmunity

Inactive Publication Date: 2015-05-27
陈泽林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there have been many reports on the treatment of cancer with traditional Chinese medicines, but the principles of using traditional Chinese medicines to treat cancer are different, and the effects of the medicines are also different. There should be ample room for exploration

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: a, get 13 grams of Phylophora clefthoofus, 9 grams of gorse root, 7 grams of Caulis vine, 11 grams of Fulong liver, and 15 grams of curcuma to make 100 mesh powder; then according to the ratio of material to liquid 1:10, Add purified water, decoct 3 times, 2 hours each time, combine the decoctions, concentrate to a relative density of 1.15-1.20 (30°C), and vacuum-dry to obtain extract A;

[0030] b. Get 17 grams of Periplaneta americana, 6 grams of Siberian greens, 15 grams of Safflower seeds, and 7 grams of honeycomb to make 100 mesh powders, add 95% ethanol at a concentration of 95% according to the ratio of solid to liquid, and extract 3 times under reflux. Combine extracts for 2 hours each time, concentrate to a relative density of 1.15-1.20 (30°C), and vacuum-dry to obtain extract B;

[0031] c. Mix extract A and extract B evenly. According to 0.45 grams one, into the capsule. Take three times a day, 4 capsules each time.

Embodiment 2

[0032] Embodiment 2: a, get 12 grams of Phyllostachys chinensis, 8 grams of gorse root, 6 grams of Caulis vine, 11 grams of Fulong liver, and 13 grams of curcuma to make 100 mesh powder; then according to the ratio of material to liquid 1:10, Add purified water, decoct 3 times, 2 hours each time, combine the decoctions, concentrate to a relative density of 1.15-1.20 (30°C), and vacuum-dry to obtain extract A;

[0033] b. Get 16 grams of Periplaneta americana, 5 grams of Sijiqing, 14 grams of Saffron, and 6 grams of honeycomb to make 100 mesh powder. According to the ratio of material to liquid 1:9, add ethanol with a concentration of 95%, and reflux extraction for 3 times. Combine extracts for 2 hours each time, concentrate to a relative density of 1.15-1.20 (30°C), and vacuum-dry to obtain extract B;

[0034] c. Mix extract A and extract B evenly. According to 0.45 grams one, into the capsule. Take three times a day, 4 capsules each time.

Embodiment 3

[0035] Embodiment 3: a, get 14 grams of Phylophora clefthoofus, 10 grams of gorse root, 8 grams of calyx, 13 grams of Fulong liver, and 15 grams of curcuma to make 100 mesh powder; then according to the ratio of material to liquid 1:10, Add purified water, decoct 3 times, 2 hours each time, combine the decoctions, concentrate to a relative density of 1.15-1.20 (30°C), and vacuum-dry to obtain extract A;

[0036] b. Get 18 grams of Periplaneta americana, 7 grams of Siberian greens, 16 grams of Safflower seeds, and 8 grams of honeycomb to make 100 mesh powders, add 95% ethanol at a concentration of 95% according to the ratio of solid to liquid, and extract 3 times under reflux. Combine extracts for 2 hours each time, concentrate to a relative density of 1.15-1.20 (30°C), and vacuum-dry to obtain extract B;

[0037] c. Mix extract A and extract B evenly. According to 0.45 grams one, into the capsule. Take three times a day, 4 capsules each time.

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PUM

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Abstract

The invention discloses a method for preparing an antitumor drug. The method comprises the following steps: (a) weighing raw materials in parts by weight, namely phellinus linteus, caragana sinica, dutchmanspipe vine, terra flava usta and zedoary, and preparing powder with the particle size of 100 meshes; then, adding pure water into the powder according to the material / liquid ratio of 1: 10, decocting for 3 times and 2 hours per time, combining decoctions, concentrating until the relative density of the combined decoction is 1.15-1.20 at the temperature of 30 DEG C, and carrying out vacuum drying, thereby obtaining an extract A; (b) weighing raw materials in parts by weight, namely periplaneta americana, Chinese holly, polygonum orientale and honeycomb, preparing powder with the particle size of 100 meshes, adding 95% ethanol into the powder according to the material / liquid ratio of 1: 9, carrying out reflux extraction for 3 times and 2 hours per time, combining extracts, concentrating until the relative density of the combined extract is 1.15-1.20 at the temperature of 30 DEG C, and carrying out vacuum drying, thereby obtaining an extract B; (c) uniformly mixing the extract A and the extract B, encapsulating the extract mixture in a manner that each capsule contains 0.45g of extract mixture, and taking three times a day and four capsules at a time.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an antitumor drug and a preparation method thereof. Background technique [0002] At present, surgery combined with radiotherapy and chemotherapy is often used in the treatment of cancer and malignant tumors. Although surgery can remove the primary lesion, when the cancer cells have metastasized beyond the primary site, the purpose of treatment cannot be achieved by excision alone, and the regeneration and metastasis of cancer cells cannot be fundamentally eliminated; radiotherapy, chemotherapy Although it can kill cancer cells, since malignant tumors form a complex entity with normal tissues and organs or adjacent tissues, normal tissue cells are damaged during treatment, and gastrointestinal reactions, bone marrow suppression, and liver, kidney and heart function damage are induced. , making the patient weaker and more difficult to treat further. Conven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/64A61K33/26
Inventor 陈泽林
Owner 陈泽林
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