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Method for manufacturing personalized nutritional compound composition based on gene polymorphism

A gene polymorphism and composition technology, which is applied in biochemical equipment and methods, microbial determination/inspection, food science, etc., can solve problems such as reducing the efficiency and willingness of use, inconvenience in taking, and users forgetting to take it. , to achieve the effect of reducing the possibility of taking the wrong quantity or frequency, reducing the frequency and volume and quality, and increasing the efficiency and willingness of use

Inactive Publication Date: 2017-06-30
TCI GENE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the development of nutrigenomics, various theories about the interaction of health, diet, and genes have been derived, such as whether nutrition intake is balanced or not is related to health and eating habits, while diet and genomics ( The composition of genomics may affect epigenomics, proteomics, and metabolomics, and the interaction between genomics and health affects life span, biological behavior, gene body itself, biomarkers, etc. , however, the existing technology is still limited by the theoretical basis, and lacks the technology that can be implemented in practice, so as to use the basis of genomics to truly regulate nutritional intake, so as to achieve the purpose of truly providing personalized nutritional formulations
[0003] In the prior art, there are pre-prepared compositions with specific formulations and dosage forms for the purpose of nutritional supplements for specific single trait variation or abnormal symptoms. However, when targeting multiple traits or symptoms, the ratio between the nutritional supplement ingredients and the carrier cannot be based on The total amount of the overall composition is adjusted, especially the pre-prepared composition is often limited by the necessary conditions for molding, and must have a certain volume and weight. When the user has multiple traits or symptoms, it must be taken at the same time. Due to the variation of traits or the combination of symptoms, it is necessary to take the composition in different dosage forms and in different quantities, which often leads to users forgetting to take it or having to pack and mark it by themselves, causing inconvenience in use; taking lozenges as an example, Users will have to take no less than dozens of lozenges every day, causing difficulty in swallowing or inconvenience in taking, thereby reducing the efficiency and willingness to use; or, for different users, different numbers of lozenges must be taken There are different dosage instructions for different users, leading to wrong or confusing instructions

Method used

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  • Method for manufacturing personalized nutritional compound composition based on gene polymorphism
  • Method for manufacturing personalized nutritional compound composition based on gene polymorphism
  • Method for manufacturing personalized nutritional compound composition based on gene polymorphism

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Embodiment

[0034] Obtain nucleic acid-containing specimen samples from voluntary subjects, using the present invention using TaqMan technology ( SNP Genotyping Assays, purchased from Applied Biosystems Inc.) to identify genotypes of single nucleotide polymorphisms. This technology is to design two probes for a SNP, design two probes with different sequences according to the normal genotype (Wild-Type) and mutant genotype (Mutant-Type) of the SNP, and pair them specifically to different two alleles. The 5' ends of the probes are labeled with different fluorescent colors, which are called reporter dyes (Reporter Dye). The fluorescent colors used for labeling are usually FAMTM dye (FAMTM dye) and VICTM dye (VICTM dye), but other fluorescent dyes can also be used systems, such as TET dyes (TET dye). The 3' end of the probe is labeled with a non-fluorescent substance that can absorb fluorescent energy, called a quencher dye (Quancher Dye), and the substance used for the label is (tetrameth...

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Abstract

The present invention provides a method for manufacturing a personalized nutrition compound combination according to gene polymorphism. The method comprises the steps of providing a detected sample, identifying the single nucleotide polymorphism of a plurality of genes of the sample to obtain an identification result; selecting the corresponding nutritional supplement component according to the identification result; mixing the above nutritional supplement components to obtain the personalized nutrition compound combination. According to the method of the present invention, the plurality of corresponding nutritional supplement components aiming at the plurality of genes can be provided according to the single nucleotide polymorphism of the plurality of genes of the sample, instead of providing the fixed multiple nutritional components based on the single gene, thereby being able to integrating and providing the nutritional supplement decision comprehensively and effectively based on the characteristics generated by the individual polygenes composition.

Description

technical field [0001] The present invention relates to a manufacturing method of a composition, in particular to a manufacturing method of a nutritional compound composition prepared according to genetic characteristics. Background technique [0002] With the development of nutrigenomics, various theories about the interaction of health, diet, and genes have been derived, such as whether nutrition intake is balanced or not is related to health and eating habits, while diet and genomics ( The composition of genomics may affect epigenomics, proteomics, and metabolomics, and the interaction between genomics and health affects life span, biological behavior, gene body itself, biomarkers, etc. However, the existing technology is still limited by the theoretical basis, and there is a lack of practically applicable and executable technology to use the basis of genomics to truly regulate nutritional intake, so as to achieve the purpose of truly providing personalized nutritional fo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/68A23L33/00
CPCA23L33/00C12Q1/6827C12Q1/6888C12Q2600/156
Inventor 施惠馨林咏翔关淑君黄雪茵
Owner TCI GENE
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