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Traditional Chinese medicine composition with capabilities of alleviating hangover and protecting liver and preparation method of traditional Chinese medicine composition

一种解酒护肝、组合物的技术，应用在解酒护肝中药组合物及其制备领域，能够解决寥寥无几等问题

Inactive Publication Date: 2015-07-22
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are very few products that can effectively relieve alcohol and protect the liver

Method used

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  • Traditional Chinese medicine composition with capabilities of alleviating hangover and protecting liver and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition with capabilities of alleviating hangover and protecting liver and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition with capabilities of alleviating hangover and protecting liver and preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～17

[0085] Examples 1-17 Preparation of anti-alcoholic and liver-protecting traditional Chinese medicine composition

[0086] Put Pueraria lobata, Hovenia dulcis, and Gardenia in an extraction tank, use 8 to 12 times the amount of water, decoct twice for 2 hours each time, extract and filter, and combine to obtain the extract;

[0087] Concentrate the extract to a relative density of 1.0 to 1.5 to obtain a concentrate;

[0088] The concentrated liquid is dried to a water content of ≤5%, crushed, and passed through a 60-100-mesh sieve to obtain the anti-alcohol and liver-protecting traditional Chinese medicine composition.

[0089] The dosages of kudzu root, Hovenia dulcis, gardenia and water are shown in Table 1:

[0090] Table 1 Examples 1-17

[0091]

[0092]

Embodiment 18

[0093] Example 18 Validation of the efficacy of the anti-alcoholic and liver-protecting traditional Chinese medicine composition provided by the present invention

[0094] 1. Materials and methods

[0095] 1.1 Experimental animals and environment: 50 male Kunming mice of SPF grade, with a body size of 18-22g, the experimental environment is a barrier environment, the temperature is 23°C-24°C, and the humidity is 50%-56%.

[0096]1.2 Dosage selection and test substance administration: the doses given to mice are 0.233g / kg bw, 0.467g / kg bw, and 1.400g / kg bw (respectively equivalent to 5, 10, and 30 times the recommended human dose) ), and a blank control group and a liver injury model control group were set at the same time. When preparing low, medium and high doses of test solutions, take the Chinese medicine compositions provided by Examples 1 to 17 of the present invention respectively, and distilled water to prepare different concentrations, as follows: low dose 11.65g / L, m...

Embodiment 19

[0122] Example 19 Preparation of Jiejiu Hugan Capsules

[0123] The prescription of Jiejiu Hugan Capsules is shown in Table 5.

[0124] Table 5 Prescription of health product capsules

[0125] type

[0126] Take the traditional Chinese medicine composition and corn starch provided in Example 17 and add them into a three-dimensional motion mixer and mix evenly for no less than 20 minutes. Use a dry granulator to granulate. Finally, add magnesium stearate and mix for 10 minutes until the materials are uniformly mixed. Discharge. Fill with No. 0 or No. 1 gelatin hollow capsules, each with a capacity of 350mg.

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Abstract

The invention relates to the technical field of traditional Chinese medicines and in particular relates to a traditional Chinese medicine composition with capabilities of alleviating hangover and protecting liver and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw herbal materials including kudzuvine roots, raisin tree seeds and gardenia and does not have obvious influence on weight of a mouse. In addition, according to the traditional Chinese medicine composition disclosed by the invention, the liver TG of an animal in a 1.400g / kg.bw dose group is obviously lower than that of a model control group, and the liver GSH is remarkably higher than that of a model control group; and in addition, the liver deformation degree of the animal in the 1.400g / kg.bw dose group is remarkably lower than that of the model control group, thus showing that the traditional Chinese medicine composition has the auxiliary protection function of liver injury caused by alcohol. The preparation method of the traditional Chinese medicine composition comprises the following steps: extracting the kudzuvine roots, the raisin tree seeds and the gardenia with water, concentrating an extract, drying, and crushing to prepare the traditional Chinese medicine composition with capabilities of alleviating the hangover and protecting the liver. According to the traditional Chinese medicine composition and the preparation method disclosed by the invention, the content of flavonoids is 800mg / 100g-1400mg / 100g.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a Chinese medicine composition for hangover and liver protection and a preparation method thereof. Background technique [0002] Wine is a mixture of various chemical components, the main components are alcohol and water, and there are many chemical substances such as acids, esters, aldehydes, alcohols, sugars, proteins, inorganic salts, trace elements, pectin, and multivitamins. China is the hometown of wine, and the wine culture has a long history since ancient times. Chinese wine has a long history of more than five thousand years and has formed its own unique style. The ancient Chinese classified the functions of wine into the following categories: wine to cure diseases, wine to support the elderly, wine to make gifts, wine to make fun, wine to forget worries, wine to strengthen courage, and wine to make people indulge, fall, and hurt the body Lost bod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P39/02A61P1/16
CPCA61K9/0056A61K9/0095A61K9/145A61K9/2054A61K9/4866A61K9/5031A61K36/488A61K36/72A61K36/744A61P1/16A61P39/02A61K2300/00
Inventor 余庆涛葛亚中马忠华李惠森
Owner INFINITUS (CHINA) CO LTD
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