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Renal nerve ablation catheter and application thereof

A technology for ablating catheters and renal nerves, which is applied in the field of ablation catheters for renal artery sympathetic nerves, can solve the problem that the surgical end point of renal artery denervation cannot be effectively mapped and measured, and the connection between stimulation function electrodes and ablation function electrodes is not disclosed. The ablation catheter cannot accurately find the nerve target and other problems, so as to shorten the ablation time, shorten the operation time and reduce the equipment cost.

Active Publication Date: 2015-07-29
SHENZHEN SALUBRIS BIOMEDICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

CN101084038A discloses a method and device for regulating renal nerves, which only has the ablation function but no mapping function; CN103284693A discloses an instrument for locating and identifying nerves in the blood vessel wall and its use method, which only has the mapping function but no ablation function
However, none of the prior art discloses how the stimulation function electrode and the ablation function electrode are connected with related equipment, and how to specifically realize the two functions
Moreover, the electrophysiological mapping catheters currently on the market are difficult to apply and risky because their structural design does not conform to the renal artery structure.
In addition, after the mapping is completed, the ablation catheter cannot accurately find the originally mapped nerve target, and the accuracy is greatly reduced
Finally, the current surgical endpoints of renal artery denervation cannot be effectively mapped and measured

Method used

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  • Renal nerve ablation catheter and application thereof
  • Renal nerve ablation catheter and application thereof
  • Renal nerve ablation catheter and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Example 1 Ablation catheter of the present invention

[0069] The technical solution of this embodiment is a single-electrode ablation catheter, such as figure 1 and figure 2 As shown, the ablation catheter 5 includes a proximal end 1 , a middle section 2 , a distal end 3 , and an electrode 4 , and also includes a sural nerve monitoring device 9 .

[0070] Among them: the elastic modulus of the material used for the proximal end 1 of the catheter is greater than that of the middle section 2, the elastic modulus of the material used for the middle section 2 is greater than that of the distal end 3, the proximal end 1 is made of polypropylene with a larger elastic modulus, and the middle section 2 is made of elastic material. The modulus is next to that of polyethylene, and the distal end 3 adopts polyimide, a material with a smaller modulus of elasticity.

[0071] Electrode 4 is a single electrode and has ablation function. First, the ablation catheter 5 is transpor...

Embodiment 2

[0073] Example 2 The ablation catheter of the present invention

[0074] The technical solution of this embodiment is a multi-electrode mapping and ablation catheter. The mapping and ablation catheter 5 includes a proximal end 1, a middle section 2, a distal end 3, and an electrode 4, as well as a sural nerve monitoring device 9. Among them, the distal end 3 can be divided into a single helix after being released, respectively as image 3 shown. Electrodes 4 with dual functions of stimulation and ablation are respectively located on the single helical structure. For multiple electrodes, each electrode is preferably connected in parallel, independent of each other, without mutual influence.

[0075] Among them: the elastic modulus of the material used for the proximal end 1 of the catheter is greater than that of the middle section 2, the elastic modulus of the material used for the middle section 2 is greater than that of the distal end 3, the proximal end 1 is made of polyp...

Embodiment 3

[0077] Example 3 The ablation catheter of the present invention

[0078] The technical solution of this embodiment is a multi-electrode mapping and ablation catheter, such as Figure 4-5 As shown, the mapping and ablation catheter 5 includes a proximal end 1, a middle section 2, a distal end 3, and an electrode 4, wherein the distal end 3 can be divided into a double helix structure or a basket structure after being released, respectively. The electrodes 4 with dual functions of stimulation and ablation are respectively located on the double helix structure or the basket structure. For multiple electrodes, each electrode is preferably connected in parallel, independent of each other, without mutual influence. In addition, the catheter further includes a saline infusion hole, which is connected to the infusion tube at the proximal end of the catheter, and the connection and use methods of other components are the same as those in Embodiment 2.

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Abstract

The invention provides a renal nerve ablation catheter to solve the problems of the prior art. The renal nerve ablation catheter comprises a sural nerve monitoring device, an ablation starting point and a finishing point of renal nerves are monitored and judged according to the excited degree of sural nerves, the renal nerve ablation catheter has double functions of mapping and ablation, ablation can be performed without repositioning bifunctional electrodes after nerve positions are mapped, accuracy and effectiveness are high, treatment time is shortened, and treatment effects are excellent according to follow-up results.

Description

technical field [0001] The invention belongs to implantable medical devices, in particular to an ablation catheter for renal artery sympathetic nerve and its application. Background technique [0002] Renal sympathetic overexcitation is a pathophysiological mechanism in diseases such as congestive heart failure, hypertension, diabetes, chronic renal failure, and cardiac arrhythmia. The use of renal sympathetic denervation to treat these diseases is fundamentally related to the reduction of sympathetic hyperactivity by this therapy, in other words, diseases based on sympathetic hyperactivity can be treated by renal sympathetic denervation . The renal sympathetic nerve is considered to be the effector and sensor of the sympathetic nerve, through which the renal sympathetic nerve can regulate the pathophysiological conditions of the cardiovascular system and other internal organs. [0003] Renal sympathetic denervation clinical trial [0004] Resistant Hypertension: Krum et ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/12
Inventor 申峰袁玲袁新胡晓露
Owner SHENZHEN SALUBRIS BIOMEDICAL ENG CO LTD