Nifedipine soft-shell capsule and preparation method thereof

A technology of dipine soft capsules and nitrobenzene, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., can solve problems such as weakening drug stability, and achieve the effects of increasing stability and maintaining appearance without fading.
CN104825418AActive Publication Date: 2015-08-12SHANGHAI SINE WANXIANG PHARMA +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI SINE WANXIANG PHARMA
Publication Date
2015-08-12

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Abstract

The invention relates to the technical fields of medicine and medicine manufacture, and especially relates to a nifedipine soft-shell capsule and a preparation method thereof. The nifedipine soft-shell capsule comprises a rubber outer layer and a content layer, an isolation layer is plated between the outer layer and the content layer, and the isolation layer is sprayed on the inner side of the outer layer. In the provided capsule, the rubber and the content are isolated by an isolation layer, thus the water and pigment in the rubber cannot be absorbed by the drugs, the stability of the drugs is increased, and the fading of the capsule is also avoided.
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Description

technical field

[0001] The invention relates to the technical field of medicine and medicine manufacture, in particular to a nifedipine soft capsule and a preparation method thereof. Background technique

[0002] Nifedipine is used for the prevention and treatment of angina pectoris caused by coronary heart disease, especially variant angina pectoris and angina pectoris caused by coronary artery spasm. It has no adverse effect on respiratory function, so it is suitable for patients with angina pectoris with obstructive airway diseases, and its curative effect is better than that of beta-receptor antagonists. It is also suitable for various types of hypertension, and has a good effect on intractable and severe hypertension. Because it can reduce afterload, it also has good curative effect on refractory congestive heart failure and is suitable for long-term use.

[0003] In the prior art, the contents of nifedipine soft capsules are hygroscopic. After being pressed into fini...

Claims

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