Pig litter size-related CNV marker and use thereof

A technology of litter size and live litter size, which is applied in the direction of recombinant DNA technology, microbial measurement/inspection, DNA/RNA fragments, etc., can solve the problems of unsuitable high-throughput detection, etc., so as to improve the economic benefits of pig raising, Easy to operate, accurate and reliable method
CN104846080AActive Publication Date: 2015-08-19CHINA AGRI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHINA AGRI UNIV
Publication Date
2015-08-19

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Abstract

The invention provides a pig litter size-related CNV marker and a use thereof. The CNV marker is a copy number variant of a pig AHR gene (GenBank: NC_010451.3) candidate region chr9: 95510416..95542790, the copy number in this region is 1 or 2, correspondingly, the pig is a copy number loss type or a normal type. Association analysis of large white pig breeding properties and copy number proves that different copy numbers of the AHR gene produce substantial influence on the pig litter size, the total litter size and live litter size of the individual with the copy number of 2 are greatly higher than those of the individual with the copy number of 1 (P is less than 0.01). The invention also provides primers for detecting the CNV marker and a kit containing the primers. The invention also provides a use of the CNV marker in identification of the types of pigs with high litter size. The CNV can be used as a very important candidate molecular marker for marker-assistant selection of large white pig litter size properties.
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Description

technical field

[0001] The invention relates to the field of livestock molecular biology detection, in particular to a CNV marker related to pig litter size and application thereof. Background technique

[0002] Pig reproductive traits are important economic traits in modern pig production, and the level of reproductive performance directly affects the production efficiency and economic benefits of pig farms. At the same time, reproductive traits are quantitative traits with low heritability and are easily affected by environmental conditions. They mainly include litter size, live litter size, birth weight, litter weight at birth, litter weight at 20 days, number of weaned cows, and weaned weight How to improve the reproductive performance of sows is the key to the healthy, efficient and sustainable development of the pig industry, and it is also the focus and hot spot of current genetic breeding research. Studying the copy number variation of genes related to pig reproduct...

Claims

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