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Processing process and manufacturing equipment of plant hollow capsules

A plant hollow capsule and processing technology, which is applied in the directions of capsule delivery, medical preparations with non-active ingredients, and drug delivery, to achieve the effects of controlling residues, reducing manual operations, and evenly absorbing materials

Active Publication Date: 2015-09-02
JIANGSU CHANGHE CAPSULE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hollow capsules prepared by using plants as the main raw materials solve the instability of gelatin hollow capsules in high temperature and cold environments, overcome the shortcomings of gelatin that is easy to react with drugs, and are convenient for long-term storage

Method used

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  • Processing process and manufacturing equipment of plant hollow capsules
  • Processing process and manufacturing equipment of plant hollow capsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] a. Take 6-8 parts of hydroxypropyl methylcellulose and 2-4 parts of gum arabic, dissolve them into an aqueous solution with a concentration of 20-35%, and stir them evenly to form a mixture.

[0043] b. Sol: Add the mixture of the above ratio into the vacuum sol tank and then add twice the amount of purified water to dissolve at high temperature. There is a feeding device on the vacuum sol tank device. The device is a stainless steel bucket, and the sol is connected with a pipe The tank is fed through the feeding device, and then the mixture is evenly sucked into the sol tank by using the vacuum on the sol tank.

[0044] c. Color matching: Make various food colorings into aqueous solutions and add them to the dissolved glue to make the required colors.

[0045] d. Static defoaming: put it in a 60-70 ℃ heat preservation bucket for 4-6 hours, and adjust the viscosity of the glue to meet the process requirements during this period.

[0046] e. Forming and drying: Put the ...

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Abstract

The present invention relates to a processing process and manufacturing equipment of plant hollow capsules, wherein a mixture of hydroxypropyl methyl cellulose and gum arabic is mainly adopted as a main raw material to prepare the plant hollow capsules, 6-8 parts of the hydroxypropyl methyl cellulose and 2-4 parts of the gum Arabic are dissolved into an aqueous solution with a concentration of 20-35%, and mixing blank making is performed to obtain the finished product. The process comprises: a, gum dissolving, b, color matching, c, standing defoaming, d, forming drying, e, cutting, f, shrinking-on, g, machine inspection, and h, packaging. According to the present invention, the plant hollow capsules and the drug powder are not subjected to the cross-linking reaction, the problems such as the dissolution rate and the gum breaking are not generated, and the capsules are not limited by the storage conditions; the hollow capsule manufacturing equipment has characteristics of uniform material suction, no agglomeration generation, manual operation and labor intensity reducing, bacterial contamination reducing, good sterilization effect, and air residue control; and the production mold can concurrently produce the products with two sizes so as to reduce the investment and the production cost.

Description

technical field [0001] The invention relates to a preparation process of hollow capsules and manufacturing equipment thereof, in particular to a preparation process of plant hollow capsules with hydroxypropylmethyl cellulose as the main raw material and manufacturing equipment used in the process. Background technique [0002] Hollow capsules have been used as drug carriers for a long time. Hollow capsules are generally made of gelatin and water. Keep the temperature at 60-75°C; filter the glue after dissolving, adjust the concentration of the glue, store and keep warm, peel and remove air bubbles, and then go through glue dipping, drying, cooling, demoulding, cutting, fitting, inspection, and packaging. into a finished product. Most of them are manual or semi-automatic production processes, which do not meet the corresponding hygienic requirements, and also waste time and increase labor costs. [0003] At present, the medicinal hollow capsules on the market are mainly pro...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K47/38A61K47/36A61J3/07
Inventor 邢继祥
Owner JIANGSU CHANGHE CAPSULE