Unlock instant, AI-driven research and patent intelligence for your innovation.

A wound dressing containing chelated silver fibers

A wound dressing and silver fiber technology, which can be used in fiber processing, medical science, textiles and papermaking, etc., and can solve the problems of short duration of antibacterial effect, inability of gel fiber to directly carry silver, poor antibacterial effect, etc.

Active Publication Date: 2018-03-20
FOSHAN UNITED MEDICAL TECH
View PDF13 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] In order to solve the disadvantages of poor antibacterial effect of wound dressings in the prior art, short duration of antibacterial effect, low hygroscopicity and wet strength, the purpose of the present invention is to provide an antibacterial wound dressing and its preparation method to solve the above problems
[0013] Especially the present invention proposes the idea of ​​blending chelated silver fibers with other non-silver gel fibers, which not only solves the difficulty that these gel fibers cannot directly carry silver, but also makes the prepared dressing containing chelated silver fibers possess Some other fiber characteristics, such as fiber hygroscopicity and gelling properties

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A wound dressing containing chelated silver fibers
  • A wound dressing containing chelated silver fibers
  • A wound dressing containing chelated silver fibers

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Example 1 Preparation of alginate chelated silver fiber dressing

[0081] Dissolve 1 gram of silver nitrate in 1000 milliliters of purified water at room temperature. After it is completely dissolved, put a 10x10 cm alginate dressing weighing 120 grams per square meter into the liquid and soak for 10 hours. After washing with water for 2 times, it is dried, then packaged and sterilized by irradiation. It is measured that the actual silver content of the dressing is 9.4% by weight, the gram weight is 120.5 grams per square meter, the hygroscopicity is 17.5 grams per 100 square centimeters, and the wet strength of the dressing is 0.6 N / cm.

[0082] The sample was cut into small pieces of 8x10mm, placed on a petri dish coated with Staphylococcus aureus, and placed in an incubator at a temperature of 37 degrees Celsius for 24 hours, and the inhibition zone was observed as follows: figure 1 shown. It can be seen that a large number of bacteria have grown on the periphery o...

Embodiment 2

[0083] Example 2 Preparation of amidoximated polyacrylonitrile polyvinyl alcohol chelated silver fiber dressing

[0084] Dissolve 10 grams of silver nitrate in 5000 milliliters of purified water. After it is completely dissolved, put 500 grams of amidoximated polyacrylonitrile polyvinyl alcohol composite (PAO / PVA) fibers (fineness 2dtex, length 38 mm) into the Soak in liquid for 9.5 hours at room temperature. Tumble dry after 2 washes. The actual silver content of the fibers was determined to be 17.9% by weight.

[0085] The prepared silver-containing PAO / PVA fiber and 990 grams of carboxymethyl cellulose fiber (length 50 mm, fineness 2.2 denier) are blended and then carded and needle-punched to make a non-woven fabric (gram weight 110 grams / square meter) , and then packaged and irradiated for sterilization. The hygroscopicity was measured to be 19 g / 100 cm2 and the wet strength to be 2.0 N / cm. Cut the sample into small pieces of 10x10 mm, place them on a petri dish coated...

Embodiment 3

[0086] Embodiment 3 prepares chitosan chelated silver fiber dressing

[0087] Dissolve 12 grams of silver nitrate in 4000 milliliters of purified water. After being completely dissolved, put 500 grams of chitosan fiber (fineness 3 dtex, length 75 mm, degree of deacetylation 92%) into the liquid and soak at room temperature 8.5 hours. Wash and dry with alcohol after 2 washes. The actual silver content of the fibers was determined to be 12.4% by weight.

[0088] The prepared silver-containing chitosan fiber is carded and needle-punched to make a non-woven fabric (gram weight 80 grams / square meter), then packaged and irradiated to sterilize. The measured hygroscopicity was 5.3 g / 100 cm2 and the wet strength was 3 N / cm.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
lengthaaaaaaaaaa
lengthaaaaaaaaaa
Login to View More

Abstract

A wound dressing containing silver chelate fibers has a single-layer structure or a multi-layer structure. The wound dressing having a single-layer structure is manufactured by blending and spinning silver chelate fibers and silver-free fibers. The wound dressing having a multi-layer structure comprises a silver chelate fabric and a silver-free fabric, and the silver chelate fabric is manufactured by blending and spinning silver chelate fibers and silver-free fibers. The weight of the silver-free fibers is 5-95 wt% of the total weight of the wound dressing. The silver chelate fibers contained in the wound dressing has a silver content of 1-35 wt%. The wound dressing has an areal weight of 25-750 g / m2, moisture absorption of 5 g / 100 cm2 and above and wet strength of 0.3 N / cm and above.

Description

technical field [0001] The invention relates to a dressing, in particular to a wound dressing containing chelated silver fibers. Background technique [0002] When caring for chronic wounds, choosing a dressing that can effectively absorb wound exudate and prevent wound infection is a key factor in treating chronic wounds. Due to the long healing period of chronic wounds, it is easy to cause wound infection during treatment, especially ulcerative wounds are most likely to produce microbial infections, which increases the healing time of wounds. A critical step in chronic wounds. [0003] At present, there are two main types of antibacterial dressings, one is to use natural antibacterial materials such as chitosan fibers, and the other is to add substances such as silver and polyhexamethylene biguanide (PHMB) to existing hygroscopic or gel materials and other antibacterial agents. Because the second wound dressing can take into account the moisture absorption and moisture ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/24A61L15/26A61L15/42A61L15/44
CPCA61L15/28A61L15/44D06M11/65
Inventor 王晓东陶炳志莫小慧姜猛进徐建军宋永娇
Owner FOSHAN UNITED MEDICAL TECH