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Suppository manufacturing method and suppository manufacturing equipment

A manufacturing method and a technology for manufacturing equipment, which are applied in the direction of making medicines into special physical or ingestible devices, can solve problems such as fragility, high labor intensity, and secondary injury to users, and achieve increased specific surface area, High degree of automation, enhanced effect of mixing effect

Active Publication Date: 2015-10-14
CHANGZHOU YUTONG DRYING EQUIP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The existing suppository manufacturing method adopts hot melting method, forms suppository product after mold casting, cooling, and demoulding, and this method step is simple, and manufacture is convenient, and cost is low; However, the mixing uniformity of this component is poor, has layering and chromatography phenomenon The specific surface area of ​​the suppository is small, which is not conducive to the release of the medicament; the strength of the suppository is poor, easy to break, and easy to break; the appearance has flashes, which affects normal use and easily causes secondary damage to the user; Convenience; manufacturing suppositories by hand is labor-intensive; the actual dose of suppositories will be affected during cold shrinkage and the waiting time for cooling will be long, resulting in low production efficiency

Method used

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  • Suppository manufacturing method and suppository manufacturing equipment
  • Suppository manufacturing method and suppository manufacturing equipment

Examples

Experimental program
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Effect test

Embodiment 1

[0026] A method of manufacturing a molded suppository, the process comprising:

[0027] a. The medicament is melted and stirred by the melting and stirring tank 7 heated by the spacer, and then sent to the centrifugal spray cooling granulator 11 for spraying. After the external air is dedusted, dehumidified and heated, dry cold air is obtained, and the quantitative feeding is carried out. The device 5 adds fine powder into the dry cold air, and then blows the dry cold air tangentially into the centrifugal spray cooling granulator from the top of the centrifugal spray cooling granulator, so that the mist medicine and the fine powder in the dry cold air are fully mixed , Cooling and granulation after bonding;

[0028] b. Sieve the medicament granules generated by cooling granulation, and sieve the granules with a particle size between 40-80 mesh as the required medicament granules, and send them into the mold and process them into suppositories by molding; sieve the powder with ...

Embodiment 2

[0032] like image 3 Shown, a kind of suppository manufacturing equipment adopting the molded suppository manufacturing method in the embodiment 1, it comprises: air filter 1, dehumidification cooler 2, heater 3, dehumidification fan 4, quantitative feeder 5, air tube 6. Melting stirring tank 7, peristaltic pump 8, conveying pipe 1 9, atomizing disc 10, centrifugal spray cooling granulator 11, conveying pipe 2 12, cyclone separator 13, conveying pipe 3 14, blower 1 16, conveying Pipe four 17, oscillating screen 18, delivery pipe five 19, blower fan two 20, pulse bag dust filter 21, delivery pipe six 22, exhaust fan 23, muffler 24.

[0033] The air filter 1 used to filter the dust in the air communicates with the dehumidification cooler 2 on the right side through the pipeline, and the dehumidification cooler 2 includes a plurality of cooling water inlets 21 in the lower part and a plurality of cooling water outlets 22 in the upper part, which can The air is dehumidified, and ...

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Abstract

The present invention relates to a suppository manufacturing method and suppository manufacturing equipment. The method comprises the simultaneous delivering of hot melt medicaments and dry cold wind with fine powder into a centrifugal spray cooling granule making machine. In this manner, medicament granules with specified diameter are prepared. The medicament granules are sent to a die and are compressed so as to get suppositories. The equipment comprises a container for hot melt medicaments and a blowing apparatus for delivering dry cold wind. The container is connected to an atomizing device at the tower top of the centrifugal spray cooling granule making machine through pipes. The blowing apparatus, connected to the centrifugal spray cooling granule making machine through the air ducts, is fit to produce swirling wind inside the centrifugal spray cooling granule making machine. A material adding device for adding fixed amount of fine powder is communicated with the air ducts. The material outlet of the centrifugal spray cooling granule making machine is connected with an oscillating sieve for sieving the medicament granules with specified diameter. According to the embodiments of the invention, the strength of the suppositories increases; the specific surface area of the suppositories enlarges; the phenomenon of layering and chromatography in the suppositories can be avoided and the outer surface of the suppositories will not have flashes.

Description

technical field [0001] The invention relates to a suppository manufacturing method and equipment, in particular to a suppository melting spray cooling granulation method and suppository manufacturing equipment. Background technique [0002] The existing suppository manufacturing method adopts hot melting method, forms suppository product after mold casting, cooling, and demoulding, and this method step is simple, and manufacture is convenient, and cost is low; However, the mixing uniformity of this component is poor, has layering and chromatography phenomenon The specific surface area of ​​the suppository is small, which is not conducive to the release of the medicament; the strength of the suppository is poor, easy to break, and easy to break; the appearance has flashes, which affects normal use and easily causes secondary damage to the user; Convenient; manufacturing suppositories by manual operation is labor-intensive; the actual dosage of suppositories is affected durin...

Claims

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Application Information

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IPC IPC(8): A61J3/08
Inventor 陆文光顾晓峰顾晓波臧德耿韩昌志
Owner CHANGZHOU YUTONG DRYING EQUIP
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