Traditional Chinese medicine composition having effects of resisting inflammation and relieving pain, preparation method and application thereof
An anti-inflammatory, analgesic and composition technology, which is applied in the directions of drug combinations, medical preparations containing active ingredients, anti-inflammatory agents, etc., to achieve the effects of easy quality control, less toxic and side effects, and specific drug potency
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Embodiment 1
[0031] (1) Preparation of Corydalis Corydalis Extract
[0032] Take 10Kg of Corydalis Corydalis, extract twice with 10 times the amount of 70% ethanol containing 3% glacial acetic acid, 3 hours for the first time, 2 hours for the second time, filter, combine the alcohol extracts twice, and recover the ethanol until it has no alcohol smell , adsorbed with 15L wet HPD-100 macroporous resin, first eluted with 30L of water, then desorbed with 75L of 60% ethanol, collected 60% ethanol eluate, recovered ethanol, and dried under reduced pressure to obtain the total alkaloids of Corydalis Corydalis . Wherein the content of tetrahydropalmatine is about 40.0%.
[0033] (2) Preparation of Aconitum aconitum extract
[0034] Take 1000g of quinine medicinal material, crush it into coarse powder, add 85% ethanol (containing 5% hydrochloric acid) to soak for 3 times, each time for 4 hours, collect the filtrate, recover the solvent under reduced pressure until there is no alcohol smell, add ...
Embodiment 2
[0037] A traditional Chinese medicine compound transdermal gel preparation containing total alkaloids of Corydalis and total alkaloids of Corydalis, the preparation method of which is as follows:
[0038] (1) Take 1 part of carbomer and add 30 parts of water to fully swell, let it stand for 12 hours, heat it in a water bath to dissolve and mix well, and obtain a transparent viscous liquid, which will be used as phase A and set aside;
[0039](2) Take 5 parts of sodium polyacrylate (NP-700), 10 parts of micro-powdered silica gel, 0.2 parts of aluminum glycinate, 1.5 parts of total alkaloids of Corydalis - total alkaloids of corydalis, dissolve with 30 parts of glycerin, and add penetration enhancer azone 1 part is stirred together to dissolve and mix well, as phase B, set aside;
[0040] (3) Add a small amount of phase A to phase B several times, stir and mix evenly, ultrasonically degas, apply it on the medical non-woven fabric while it is hot, let it dry naturally, until the ...
Embodiment 3
[0042] A traditional Chinese medicine compound transdermal gel preparation of total alkaloids of Corydalis and total alkaloids of Corydalis, the preparation method of which is as follows:
[0043] (1) Take 1 part of carbomer and add 50 parts of water to fully swell, let it stand for 12 hours, heat it in a water bath to dissolve and mix well, and obtain a transparent viscous liquid, which will be used as phase A and set aside;
[0044] (2) Take 10 parts of sodium polyacrylate (NP-700), 5 parts of micro-powdered silica gel, 0.5 part of aluminum glycinate, 1 part of the composition of total alkaloids of Corydalis and total alkaloids of corydalis, dissolve it in 40 parts of glycerin, and add the penetration enhancer azone Stir the 2 parts together to dissolve and mix well, as phase B, set aside;
[0045] (3) Add a small amount of phase A to phase B several times, stir and mix evenly, ultrasonically degas, apply it on the medical non-woven fabric while it is hot, let it dry natural...
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