Application of fingerprint spectrum consisting of microRNAs in diagnosis and treatment of human ovarian cancer

A technology for ovarian cancer and ovarian cells, applied in the field of small RNA (miRNA), can solve the problems of difficult diagnosis and effective treatment of ovarian cancer
CN104975019AActive Publication Date: 2015-10-14SHANGHAI XIANGQIONG TECHNOLOGY LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI XIANGQIONG TECHNOLOGY LTD
Publication Date
2015-10-14

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Abstract

The invention relates to an application of a fingerprint spectrum consisting of microRNAs in the diagnosis and treatment of human ovarian cancer. The fingerprint spectrum consisting of multiple microRNAs can be used for distinguishing ovarian tissue from ovarian cancer tissue very effectively, has high sensitivity and specificity and can be effectively applied to the ovarian cancer diagnosis, tumor grading and prognosis evaluation.
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Description

technical field

[0001] The invention discloses the use of small RNA (miRNA; microRNA) fingerprints in the diagnosis of ovarian cancer, and belongs to the technical fields of biomedicine, bioengineering and detection. Background technique

[0002] Malignant tumor of the ovary is one of the common malignant tumors of the female reproductive organs, and its incidence ranks third after cervical cancer and uterine body cancer (Jemal et al.; 2011). However, the mortality rate of epithelial ovarian cancer ranks first in all types of gynecological tumors, posing a serious threat to women's lives. Due to the complex embryonic development, tissue anatomy and endocrine function of the ovary, and the atypical early symptoms, it is quite difficult to distinguish the tissue type and benign from malignant ovarian tumors before operation. Among ovarian malignancies, epithelial carcinoma is the most common, accounting for about 80%-90% of ovarian cancers (Chan et al; 2006), followed by mali...

Claims

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