Process for fast preparing DAST crystals in ethanol solution
A technology of ethanol solution and preparation process, applied in the direction of organic chemistry, etc., can solve the problems of adverse effects on the operator's body and ecological environment, long process cycle, limited number of crystallization equipment and crystal yield in application research, so as to avoid adverse effects, Effects of reducing pollution and avoiding harm
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Embodiment 1
[0010] Example 1: In an argon atmosphere, weigh 1.2502g of DAST source powder and place it in a 500mL round bottom flask, then pour 248.75g (approximately 314.9mL) of absolute ethanol into it, heat it under full stirring until the source powder is completely dissolved, and prepare A concentration of 0.5wt% DAST ethanol solution. Transfer the DAST solution into a 500mL jar while hot, seal it with a rubber stopper and take the jar out of the argon environment. Place the jar in a temperature-controlled water bath with a temperature control accuracy of ±0.05°C and a constant temperature of 21°C. After the DAST solution is stable and consistent with the temperature of the water bath, start the cooling program and control the cooling rate to 3°C / d. After 5 days, the available size is (1-4)×(1-4)×(0.2-1.0) mm 3 50 pieces of DAST crystals.
Embodiment 2
[0011] Example 2: In a helium atmosphere, weigh 2.5003g of DAST source powder and place it in a 500mL round bottom flask, then pour 247.5g (approximately 313.3mL) of absolute ethanol into it, heat it under full stirring until the source powder is completely dissolved, and prepare into a DAST ethanol solution with a concentration of 1.0 wt%. Transfer the DAST solution into a 500mL jar while hot, seal it with a rubber stopper and take the jar out of the helium environment. Place the jar in a temperature-controlled water bath with a temperature control accuracy of ±0.05°C and a constant temperature of 33°C. After the DAST solution is stable and consistent with the temperature of the water bath, start the cooling program and control the cooling rate to 4°C / d. After 4 days, the available size is (1-5)×(1-5)×(0.2-1.2) mm 3 36 pieces of DAST crystals.
Embodiment 3
[0012] Example 3: In an argon atmosphere, weigh 7.0006g of DAST source powder and place it in a 1000mL round bottom flask, then pour 493g (approximately 624mL) of absolute ethanol into it, heat it under full stirring until the source powder is completely dissolved, and prepare the concentration It is 1.4wt% DAST ethanol solution. Transfer the DAST solution into a 1000mL jar while hot, seal it with a rubber stopper and take the jar out of the argon environment. Place the jar in a temperature-controlled water bath with a temperature control accuracy of ±0.05°C and a constant temperature of 41°C. After the DAST solution is stable and consistent with the temperature of the water bath, start the cooling program and control the cooling rate to 1°C / d. After 18 days, the available size is (2-4)×(2-4)×(0.5-0.9) mm 3 12 pieces of DAST crystals.
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