Preparation method of compound kudzuvine root extract

Abstract

The invention provides a preparation method of a compound kudzuvine root extract. The preparation method comprises the following steps: S1. adding 7-9 times of a methanol or ethanol solution of 90% to kudzuvine root by volume, heating and reflux-extracting for 3-5h; separating solid and liquid; recovering the methanol or ethanol solution so that an extract is in the form of a thick paste; and then, extracting the extract by virtue of water saturated n-butyl alcohol for 2-5 times; recovering a solvent; and concentrating and drying the extract in a vacuum so as to obtain a kudzuvine root extract; S2. heating and reflux-extracting soybean meal by virtue of an ethanol solution of 93% for 2-4h; separating solid and liquid; recovering the ethanol solution until an extract is in the form of a thick paste; and then, extracting the extract by virtue of water saturated n-butyl alcohol for 4-6 times; recovering a solvent; and concentrating and drying the extract in a vacuum so as to obtain daidzin; and S3. mixing the kudzuvine root extract and daidzin at the ratio of (1-5): 1 so as to obtain a compound kudzuvine root extract product. The preparation method disclosed by the invention has the beneficial effect that the content of daidzin in the extract is greatly improved.

Description

technical field [0001] The invention relates to a preparation method of an extract, in particular to a preparation method of a compound kudzu root extract. Background technique [0002] The natural plant kudzu root has very special medicinal value. It has good curative effect on cardiovascular and cerebrovascular diseases, and has quite good alcohol abstinence and hangover effects. The latest research has found that these medicinal effects of puerarin are mainly due to its two components, puerarin and daidzein. Puerarin and daidzein have their own special effects in medicine, and both are indispensable. The prior art generally adopts the following processes when preparing the kudzu root extract: kudzu root plant→methanol extraction→extract→water-saturated n-butanol extraction or Al 2 o 3 Separation on the column → extract or eluent → recovery of solvent → residue → vacuum concentration and drying → kudzu root extract. In the extract prepared by this method, the content of...

AI Technical Summary

Problems solved by technology

In the extract prepared by this method, the content of daidzein is very small, and it is difficult to exert the best medicinal effect in application

Moreover, since there is no requirement for the content of daidzein, there is no item of daidzein in the quality control index of kudzu root extract in the prior art. Therefore, the content of daidzein in each batch of products may vary, which makes the drug effect sometimes good and sometimes bad. Bad, the treatment effect is unstable