Supercharge Your Innovation With Domain-Expert AI Agents!

Traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation, can solve the problems of increasing production cost and process complexity, risks caused by consumers' health and safety, and achieve the effect of reducing the content

Active Publication Date: 2015-11-18
CHENGDU HUASUN GRP INC LTD +1
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although there are many kinds of traditional Chinese medicine liver protection health care products on the market, there are too many kinds of traditional Chinese medicine used in these products. In other words, too many components of traditional Chinese medicine will also increase the production cost and process complexity. Therefore, how to achieve auxiliary protection against alcoholic liver injury with fewer components of traditional Chinese medicine is a promising research direction

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1: the preparation of the traditional Chinese medicine composition of the present invention

[0040] 1. Preparation of Notoginseng Saponins

[0041] Clean the Panax notoginseng (head), control the temperature at 55-60°C, dry it to the touch without moisture, pulverize it into powder, soak it in 60% ethanol for ≥24h, then put it in a cylinder and start percolating, and control the flow rate to 5-8ml / min kg of medicinal materials, collect Panax notoginseng leachate, concentrate the Panax notoginseng leachate to a specific gravity of 1.08-1.12 to obtain a paste, the concentration temperature is ≤ 70 °C, and then add water and stir to form a Panax notoginseng aqueous solution and use macroporous adsorption resin chromatography;

[0042] The flow rate of the aqueous solution of Panax notoginseng on the column is ≤600L / h. After the column is applied, first wash with water at 800L / h for half an hour, then wash with water at 1200L / h for half an hour, and finally was...

Embodiment 2

[0053] Example 2: Preparation of Hugan Tablets

[0054] Mix 25 parts Pueraria lobata extract, 10 parts Salvia miltiorrhiza extract, 150 parts notoginseng glycol saponins, 60 parts microcrystalline cellulose, 120 parts pregelatinized starch, 120 parts dextrin with a three-dimensional mixer for 10 minutes; then use 16 parts 14% starch slurry was prepared by the starch cooking method; the starch slurry was mixed with the above mixture, and wet granulation was carried out with a swinging oscillating sieve; The moisture of the granules (less than 10%) was checked by the instrument; 2.5 parts by weight of magnesium stearate was added for blending and tableting; and then film coating was performed.

Embodiment 3

[0055] Example 3: Security Detection

[0056] 1. Experimental animals: 20 SPF SD rats, half male and female, weighing 180-220 g; 20 SPF Kunming mice, half male and half, weighing 18-22 g, all provided by Chengdu Dashuo Biotechnology Co., Ltd. Certificate number: SCXK (Chuan) No. 2008-24. Quarantine for one week before the test. During the whole test process, the animals had free access to food and water, the room temperature was 21°C to 24°C, and the relative humidity was 50% to 65%.

[0057] 2. Test method

[0058] Acute oral toxicity test in rats: The Chinese medicinal composition 1 of the present invention was used as the detection object, and the maximum tolerated dose method was adopted. There were 10 male and 10 SD rats in each group. Sample preparation: Accurately weigh 50g of the sample, dissolve it in distilled water and prepare it to 200ml, and give 2.0ml / 100g.bw to the animal by oral gavage twice on an empty stomach, with an interval of 4h. After gavage, the sym...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of traditional Chinese medicine health products and discloses a traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition is composed of pseudo-ginseng diol saponin, a salvia miltiorrhiza extractive and a kudzuvine root extractive; the salvia miltiorrhiza extractive and the kudzuvine root extractive are obtained through reflux extraction by ethyl alcohol. According to the invention, pseudo-ginseng, salvia miltiorrhiza and kudzuvine root are selected as Chinese herbal compounds, the novel traditional Chinese medicine composition is obtained by adopting a modern extraction technology, the auxiliary protection function of reducing alcoholic liver injury can be realized through fewer components, particularly, the phenomenon that the contents of triglyceride and very low density lipoprotein increase caused by alcoholic liver injury is reduced obviously and the traditional Chinese medicine composition can be applied to preparation of drugs and health products for protecting the liver.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine health products, in particular to a traditional Chinese medicine composition and a preparation method and application thereof. Background technique [0002] At present, my country is one of the countries with a high incidence of liver disease. Finding and researching effective drugs for the treatment of liver disease has always been the wish of the majority of scientific researchers and has been paid more and more attention. more people's attention. [0003] Traditional Chinese medicine health products are favored by consumers because of their small side effects. There are many traditional Chinese medicine health products on the market that help to reduce chemical liver injury (alcoholic liver injury), such as various commercially available products recorded in Table 1: [0004] Table 1 [0005] [0006] Although there are many kinds of traditional Chinese medicine liver-protecting...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A23L1/29A61P1/16A23L33/00
Inventor 杨华蓉王莉曹科张天洋高星卢瀚思
Owner CHENGDU HUASUN GRP INC LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com