Detection primers, probes and kits for 16 types of hpv virus

An HPV virus and kit technology, which is applied in the field of detection primers, probes and kits for 16 types of HPV viruses, can solve the problem of inability to detect multiple types of HPV viruses at the same time.
CN105087827BActive Publication Date: 2018-03-02北京鑫诺美迪基因检测技术有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
北京鑫诺美迪基因检测技术有限公司
Publication Date
2018-03-02

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Abstract

The invention discloses a primer, probe and kit for detecting type-16 HPV (human papillomavirus). The primer and the probe are suitable for screening the HPV related diseases quickly, accurately and simply, do not cross-react with other viruses, are capable of detecting common high and low risk types of HPVs, two types of HPVs and 14 types of HPVs in total, cover a wide range of high risk types of HPVs and are more accurate and complete in detection than kits in the present market. The kit further comprises negative, positive and weakly positive quality controls and helps further increase detection accurateness.
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Description

technical field

[0001] The invention relates to detection primers, probes and kits for 16 types of HPV viruses. Background technique

[0002] Human papillomavirus (HPV) is a small non-enveloped DNA virus belonging to the papillomavirus family. Virus particles are composed of single copy DNA and protein, and have a double-stranded closed-circle DNA genome with a size of about 8000bp. The genome consists of three gene regions, including the early region (Early Region, E) containing 8 early open reading frames, with 2 The late region (Late Region, L) of the late open reading frame and the non-coding long control region (Long Control Region, LCR). The early region encodes proteins related to HPV replication, transcription, and cell transformation; the late region encodes HPV structural proteins, such as the major capsid protein L1 and the minor capsid protein L2 that make up the viral capsid. The essential difference between the various types of HPV lies in the difference in t...

Claims

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