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Halogenated butyl rubber membrane covering rubber plug for injection

A halogenated butyl rubber and brominated butyl rubber technology is applied in the field of halogenated butyl rubber film-coated rubber stoppers for injection, which can solve the problems of low service life, poor environmental protection, difficulty in preparing medical rubber products, etc. Cap cost, effect of reducing puncture force and chance of chipping

Inactive Publication Date: 2016-02-03
ANHUI ZHONGMA RUBBER & PLASTIC PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Under the conditions of high temperature and high pressure, traditional medical rubber products tend to produce exudates and volatiles that pollute the human body and pharmaceuticals in their vulcanization system, making it difficult to prepare medical rubber products that meet the highest quality standards for pharmaceuticals
Existing medical rubber products and preparation methods thereof have complicated process, poor product environmental protection, weak use safety, and low service life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0022] Specific embodiment 1: the halogenated butyl rubber coated rubber stopper for injection has the following components:

[0023] 60 parts of bromobutyl rubber, 30 parts of calcined kaolin, 3 parts of zinc oxide, 89 parts of E-42 epoxy resin, 89 parts of phenolic-butadiene rubber copolymer, 66 parts of acetone, 10 parts of ethylenediamine, 100 parts of soybean protein 5 parts of turpentine, 15 parts of 50% sodium hydroxide aqueous solution, 40 parts of lime water, 400 parts of chrysanthemum water, 10 parts of toilet water, 30 parts of flower rhizomes, 5 parts of ginseng, 5 parts of Atractylodes macrocephala, 5 parts of raw grain buds, 50 parts of water 5 parts, Jiaohawthorn 5 parts, Divine Comedy 5 parts, Polygonatum 5 parts, Aracea 9 parts, Calamus 15 parts, sawdust 15 parts, tofu water 100 parts.

specific Embodiment 2

[0024] Specific embodiment 2: the halogenated butyl rubber coated rubber stopper for injection has the following components:

[0025] 70 parts of bromobutyl rubber, 40 parts of calcined kaolin, 5 parts of zinc oxide, 99 parts of E-42 epoxy resin, 99 parts of phenolic-butadiene rubber copolymer, 75 parts of acetone, 15 parts of ethylenediamine, 120 parts of soybean protein 7 parts of turpentine, 20 parts of 50% sodium hydroxide aqueous solution, 50 parts of lime water, 450 parts of chrysanthemum water, 20 parts of toilet water, 50 parts of flower rhizomes, 10 parts of ginseng, 10 parts of Atractylodes macrocephala, 10 parts of raw grain buds, 60 parts of water 10 parts of Jiao Hawthorn, 10 parts of Divine Comedy, 7 parts of Polygonatum Polygonatum, 12 parts of Araceae, 18 parts of Calamus, 18 parts of sawdust, and 120 parts of tofu water.

[0026] The preparation method of the halogenated butyl rubber-coated stopper for injection mainly includes the following steps:

[0027] T...

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PUM

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Abstract

A halogenated butyl rubber membrane covering rubber plug for injection is prepared from 60-70 parts of brominated butyl rubber, 30-40 parts of calcined kaolin, 3-5 parts of zinc oxide, 89-99 parts of epoxy resin E-42, 89-99 parts of phenol-nitrile butadiene rubber copolymers, 66-75 parts of acetone, 10-15 parts of ethidene diamine, 100-120 parts of soybean protein, 5-7 parts of turpentine, 15-20 parts of 50% sodium hydroxide aqueous solution, 40-50 parts of whitewash, 400-450 parts of chrysanthemum water, 10-20 parts of floral water, 30-50 parts of flower and plant roots and stems, 5-10 parts of ginseng, 5-10 parts of atractylodes macrocephala koidz, 5-10 parts of raw rice sprouts, 50-60 parts of water, 5-10 parts of scorched hawthorn fruit, 5-10 parts of medicated leaven, 5-7 parts of radix polygonati officinalis, 9-12 parts of rhizoma arisasmatis, 15-18 parts of calamendiol, 15-18 parts of wood bits and 100-120 parts of soycheese water. The rubber plug has the advantages that the rubber plug prepared through the process can make direct contact with medicine, an inner cover of a combined cover can be omitted, the penetration force and the chipping falling rate are decreased, and cover assembling cost is reduced for pharmaceutical factories as well.

Description

Technical field: [0001] The invention relates to the technical field of pharmaceutical rubber manufacturing methods, in particular to a halogenated butyl rubber-coated rubber stopper for injection. Background technique: [0002] With the development of society, there are more and more types of rubber products used in the medical and health field, such as rubber stoppers for various pharmaceutical bottles, pistons for sterile syringes, sealing rubber seals for injections, hoses, catheters, medical air cushions, sterilization Rubber medical gloves, baby pacifiers, blood transfusion tubes, etc. Ideal medical rubber products not only need to have good physical properties, but also must be non-toxic and chemically inert. In particular, rubber products in the body should have the characteristics of not causing disease, not damaging adjacent tissues, not causing allergies, and having good aging properties. [0003] Under the conditions of high temperature and high pressure, the vu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L89/00C08L63/00C08L61/14C08L23/28C08K13/02C08K3/34C08K3/22C08K5/07C08K5/17B65D51/00
Inventor 张艳
Owner ANHUI ZHONGMA RUBBER & PLASTIC PROD
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