a drug for arthritis

A technology for knee osteoarthritis and drugs, which can be used in drug combination, drug delivery, drug formulation and other directions, and can solve problems such as unfavorable drug production and application, and many drug components.

Active Publication Date: 2019-11-29
上海市浦东新区上钢社区卫生服务中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the current effective traditional Chinese medicine for the treatment of osteoarthritis, there are too many components of the medicine, which is not conducive to the production and application of the medicine; moreover, it often causes skin allergy symptoms such as itching and rash

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] crude drug components

[0031]

[0032] fine drug components

[0033] Camphor 100g Menthol 40g Wintergreen Oil 150g

[0034] Grind camphor and menthol to co-melt.

[0035] dressing components

[0036] Sodium benzoate 4.58g lanolin 114.5g petrolatum about 1000g

[0037] drug preparation

[0038] Take 2000g of crude drug components, add water and decoct twice, each time with 10 times the water, decoct for 1 hour, the decoction time starts from boiling, and the decoction process can be kept at a slight boil. Soak for 0.5h before the first decoction.

[0039] After each decoction, filter through a 300-mesh filter cloth, combine the second decoction, and concentrate under reduced pressure to 2:1 (g:mL, that is, each mL is equivalent to 2g of crude drug).

[0040] Cool to room temperature, add 1 times ethanol for precipitation, let stand for 24 hours, filter the supernatant, recover ethanol under reduced pressure to a relative density of 1.20-1.25 (50°C-60°C), and ob...

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Abstract

The invention discloses medicine for treating arthritis and a preparation method thereof. The medicine comprises, by weight, 300-700 parts of cercis chinensis, 300-700 parts of negundo chastetree fruit, 100-200 parts of fructus gardeniae, 50-150 parts of coxtex moutan, 100-300 parts of rheum officinale, 100-200 parts of semen strychni, 50-150 parts of radix paeoniae rubra, 50-150 parts of radix angelicae pubescentis, 50-150 parts of cortex acanthopanacis, 50-150 parts of rhizoma arisaematis, 50-150 parts of camphor, 20-50 parts of menthol and 50-150 parts of wintergreen oil. The medicine for treating the arthritis has the advantages that medicine components are simplified, the camphor and menthol are added to increase the local effect of percutaneous absorption of traditional Chinese medicine materials, traditional Chinese medicine external treatment is combined with the modern percutaneous technology to form a traditional Chinese medicine percutaneous treatment system, and the medicine is low in toxic and side effects, has certain pharmacological activity, combines treatment and percutaneous absorption promoting and conforms to the trend of returning to nature.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a medicine for treating arthritis. Background technique [0002] Osteoarthritis (OA) is a joint disease caused by degeneration of articular cartilage and mainly manifested by bone hyperplasia. It is a common disease in middle-aged and elderly people. Knee osteoarthritis is the The category with the highest clinical incidence. With the prolongation of human life span and the aging of social population, its incidence rate increases year by year. [0003] In addition to symptomatic treatment, symptom relief and artificial joint replacement, there is still a lack of effective methods for the clinical treatment of this disease in western medicine. In terms of symptomatic treatment, there is currently no specific treatment in Western medicine. Long-term use of non-steroidal drugs will cause more serious side effects, including gastric ulcer, gastric bleeding, and even liver and kidne...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8884A61K47/44A61K47/10A61K47/08A61P19/02A61P19/08A61K31/125A61K31/045
CPCA61K9/0014A61K9/06A61K31/045A61K31/125A61K36/185A61K36/232A61K36/254A61K36/48A61K36/56A61K36/65A61K36/708A61K36/71A61K36/744A61K36/85A61K36/8884A61K47/08A61K47/10A61K47/44A61K2236/331A61K2300/00
Inventor 奚鸿昌石仰山
Owner 上海市浦东新区上钢社区卫生服务中心
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