Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of traditional Chinese medicinal motherwort decoction-free preparation

A technology of motherwort and free decoction, which is applied in the field of preparation of traditional Chinese medicine motherwort free decoction, can solve the problems of complicated operation and incomplete active ingredients, and achieve the effect of increasing the content

Inactive Publication Date: 2016-03-02
HENAN XINGZHI PATENT SERVICE CO LTD
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The scheme provided by this invention uses CO2 to extract in stages, which achieves the purpose of extracting by multiple different methods and improving the extraction rate, but the operation is relatively complicated, and it cannot overcome the defect that the active ingredients of the drug are not comprehensively extracted by a single extractant

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of traditional Chinese medicinal motherwort decoction-free preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method of traditional Chinese medicine motherwort free decoction, comprising the following steps:

[0029] 1) Pretreatment: Wash fresh motherwort in flowering stage, coarsely powder it to a particle size of 90 mesh, and superfine powder to a particle size of 0.15 μm;

[0030] 2) extracting the superfine powder Leonurus granules obtained in step 1) by immersion in hydrochloric acid, the specific extraction process is: soaking and extracting with 0.5wt% hydrochloric acid solution as a solvent, extracting for 2 hours at a material-to-liquid ratio of 1:8, standing, and filtering. Collect the supernatant, extract the filter residue with a solid-liquid ratio of 1:5 for 1 hour, let stand, filter, collect the supernatant, and extract the filter residue with a solid-liquid ratio of 1:3 for 0.5 hour, combine the extracts to concentrate, and set aside.

[0031] 3) Step 2) the resulting extraction residue SFE-CO 2 method extraction, the specific process is: first use...

Embodiment 2

[0035] A preparation method of traditional Chinese medicine motherwort free decoction, comprising the following steps:

[0036] 1) Pretreatment: Wash fresh motherwort in flowering stage, coarsely powder it to a particle size of 100 mesh, and superfine powder to 0.75 μm;

[0037] 2) extracting the superfine motherwort granules obtained in step 1) by immersion in hydrochloric acid, the specific extraction process is to soak and extract with 1wt% hydrochloric acid solution as a solvent, extract for 3 hours with a solid-liquid ratio of 1:10, stand still, filter, and collect The supernatant and filter residue were extracted for 1.5 hours at a solid-liquid ratio of 1:6, left to stand, filtered, and the supernatant collected, and the filter residue was extracted for 1.0 hour at a solid-liquid ratio of 1:4, and the combined extracts were concentrated and set aside.

[0038] 3) Step 2) the resulting extraction residue SFE-CO 2 method extraction, the specific process is: first use 1.5 ...

Embodiment 3

[0042] A preparation method of traditional Chinese medicine motherwort free decoction, comprising the following steps:

[0043] 1) Pretreatment: Wash fresh motherwort in flowering stage, coarsely powder it to a particle size of 95 mesh, and superfine powder to 0.55 μm;

[0044] 2) extracting the superfine powder Leonurus granules obtained in step 1) by immersion in hydrochloric acid, the specific extraction process is: soaking and extracting with 0.8wt% hydrochloric acid solution as a solvent, extracting for 2.5 hours with a solid-liquid ratio of 1:9, standing, and filtering. Collect the supernatant, extract the filter residue with a solid-liquid ratio of 1:5.5 for 1.2 hours, let stand, filter, collect the supernatant, and extract the filter residue with a solid-liquid ratio of 1:3.5 for 0.9 hours, combine the extracts and concentrate ,spare.

[0045] 3) Step 2) the resulting extraction residue SFE-CO 2 extraction method, the specific process is: first use 1.2 times the weight...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle size (mesh)aaaaaaaaaa
particle size (mesh)aaaaaaaaaa
particle size (mesh)aaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of a traditional Chinese medicinal motherwort decoction-free preparation. Preferably, the preparation is obtained by medicinal material coarse grinding, medicinal material superfine grinding, combination of weak acid decocting-soaking extraction and supercritical extraction, concentration of extracts for later use, freeze-drying, addition of adjuvant materials, and uniformly mixing. Through superfine grinding, active ingredients of the medicines are better dissolved out, and in combination with the weak acid decoction and the supercritical extraction, the active ingredients of the medicines are extracted fully and thoroughly; the preparation method of the decoction-free motherwort particles disclosed by the invention is simple in step, free from toxic and side effects and more obvious in efficacy; and the prepared motherwort particles are convenient to carry and are capable of meeting clinical requirements on the product.

Description

technical field [0001] The invention belongs to the field of pharmacy, and in particular relates to a preparation method of traditional Chinese medicine motherwort free decoction. Background technique [0002] Motherwort and its preparations are traditional Chinese medicines in my country. They have been used by the general public for thousands of years. They are recorded and included in medical books of all dynasties and Chinese Pharmacopoeia. Many preparations are listed as national basic medicines. Applied clinically. Though the new dosage form of Motherwort preparation is constantly being developed, new process, new technology are constantly applied. But it still feels that there are many shadows of tradition and few modern things. Motherwort and its preparations have been called "the holy medicine of gynecology" and "good medicine for multipartum" by doctors and scholars. Encourage the development of new preparations of Motherwort and the research and promotion of ext...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61K36/533A61K47/40A61P15/00A61K31/7016A61K35/36
Inventor 马新攀
Owner HENAN XINGZHI PATENT SERVICE CO LTD