Two optically pure isomers of NK007 and bactericidal applications

Abstract

The invention relates to two optically pure isomers of NK007 for short and applications in a bactericidal aspect. Compounds NK007-3 and NK007-4 have good bactericidal activity, can be used for treating plant bacteria diseases selected from fusarium wilt of cucumber, cercospora brown spot of peanut, apple ring spot, alternaria solani, puccinia polysora, rice bakanae disease, sclerotinia rot of colza, phytophthora capsici disease, wheat sharp eyespot, bipolaris maydis, watermelon anthracnose, potato late blight, rice sheath blight disease and cucumber gray mold.

Description

technical field

[0001] The present invention relates to two optically pure isomers called NK007 for short and their application in the field of sterilization. Background technique

[0002] The structural formula of the compound referred to as NK007 is:

[0003]

[0004] Chirality is a basic feature of life processes, macromolecules as an important basis for life activities. Such as nucleic acids, proteins, polysaccharides, etc. all have chirality: when a chiral drug enters a living body, its two enantiomers usually exhibit different biological activities. Due to the lack of awareness of this, human beings have learned a painful lesson before. For example, a drug developed by a German pharmaceutical company in the 1950s to treat the early discomfort of pregnant women—the drug was very effective, but it was soon discovered that many babies born to pregnant women who took the drug had mutilated limbs. Later, it was found that one configuration of thalidomide has a teratog...

Images