Propranolol hydrochloride smearing preparation and preparation method and application thereof

Abstract

The invention provides a propranolol hydrochloride smearing preparation and a preparation method and application thereof. The propranolol hydrochloride smearing preparation is prepared from, by weight, 1%-8% of propranolol hydrochloride, 2.5%-15% of substrate, 2%-10% of skin penetration enhancer, 3%-16% of moisturizing agent, 0.02%-0.2% of bacteriostatic agent and the balance water. The propranolol hydrochloride smearing preparation is small in skin irritation and capable of directly acting on infantile hemangioma ulcer parts to rapidly facilitate ulcer healing and treating hemangioma simultaneously.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular, the invention relates to a propranolol hydrochloride varnish and a preparation method and application thereof. Background technique [0002] Ulcer is the most common complication of hemangioma, with an incidence rate of 5% to 15%. During the period of rapid growth of infantile hemangioma, immersion and friction can easily cause ulcers, and then lead to bleeding, infection, etc. If not treated in time and effectively, the ulcer will leave a deformed appearance that is difficult to repair after healing, and even cause visceral function Sexual disorder brings great pain to children, so clinically it tends to actively treat ulcers in the early stage. At present, there is no special drug or treatment method for infantile hemangioma ulcer. Traditional treatment methods for hemangioma such as laser, oral medicine and local administration of hormones are mainly used for treatment, but th...

AI Technical Summary

Problems solved by technology

However, the current oral propranolol may still cause side effects such as hypotension, hypoglycemia, and bradycardia.

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