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Stirring device and container for preparing colloid class plasma solubilizer

A technology of stirring device and solubilizing agent, which is applied in the direction of mixer with rotating stirring device, dissolution, transportation and packaging, etc., and can solve problems affecting product qualification rate and so on

Active Publication Date: 2016-04-13
吉林省长源药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the diversification of the molecular weight leads to the reaction efficiency of the subsequent acylation reaction and affects the qualified rate of subsequent products

Method used

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  • Stirring device and container for preparing colloid class plasma solubilizer
  • Stirring device and container for preparing colloid class plasma solubilizer
  • Stirring device and container for preparing colloid class plasma solubilizer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Supplied with double deck combination paddles. The upper mixing paddle is a variable cross-section two-blade oblique paddle, the front and rear edges of the main paddle are serrated, the sawtooth height is 15mm, and the included angle between the small paddle and the main paddle is 45°; Narrow-bladed airfoil blades, the height of the sawtooth on the rear edge of the blade is 15mm. Assemble the double-layer combined paddle with the 1800L concentrated tank and fix it on the stirring shaft. The ratio of the diameter of the paddle to the inner diameter of the tank is 0.4:1. see Figure 5 , Figure 5 It is a schematic structural diagram of the gelatin concentration tank provided in Example 1 of the present invention, wherein, 1 is a motor and a reducer, 2 is a coupling, 3 is a reducer frame, 4 is a double-end mechanical seal, and 5 is a reducer Machine base, 6 is a stirring shaft, 7 is a variable cross-section two-blade oblique paddle, and 8 is a three-narrow-blade airfoi...

Embodiment 2

[0074] Supplied with double deck combination paddles. The upper mixing paddle is a variable cross-section two-bladed oblique paddle, the front and rear edges of the main paddle are serrated, the sawtooth height is 14.5mm, and the included angle between the small paddle and the main paddle is 44.5°; the bottom paddle is Three narrow-blade airfoil blades, the sawtooth height of the rear edge of the blade is 14.5mm. Assemble the double-layer combined paddles with the 1500L concentrated tank and fix them on the stirring shaft. The ratio of the length of the paddle to the inner diameter of the tank is 0.3:1. see Figure 5 , Figure 5 It is a schematic structural diagram of the gelatin concentration tank provided in Example 1 of the present invention, wherein, 1 is a motor and a reducer, 2 is a coupling, 3 is a reducer frame, 4 is a double-end mechanical seal, and 5 is a reducer Machine base, 6 is a stirring shaft, 7 is a variable cross-section two-blade oblique paddle, and 8 is ...

Embodiment 3

[0082] Supplied with double deck combination paddles. The upper mixing paddle is a variable cross-section two-blade oblique paddle, the front and rear edges of the main paddle are serrated, the sawtooth height is 15.5mm, and the included angle between the small paddle and the main paddle is 45.5°; the bottom paddle is Three narrow-blade airfoil blades, the sawtooth height of the rear edge of the blade is 15.5mm. Assemble the double-layer combination paddle with the 2000L concentrated tank and fix it on the stirring shaft. The ratio of the length of the paddle to the inner diameter of the tank is 0.5:1. see Figure 5 , Figure 5 It is a schematic structural diagram of the gelatin concentration tank provided in Example 1 of the present invention, wherein, 1 is a motor and a reducer, 2 is a coupling, 3 is a reducer frame, 4 is a double-end mechanical seal, and 5 is a reducer Machine base, 6 is a stirring shaft, 7 is a variable cross-section two-blade oblique paddle, and 8 is a...

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Abstract

The invention provides a stirring device for preparing colloid class plasma solubilizer. The stirring device comprises a stirring shaft and double layers of combination blades which are fixed to the stirring shaft; the double layers of combination blades comprise a bottom layer of stirring blades and an upper layer of stirring blades, the bottom layer of stirring blades are fixed to one end of the stirring shaft, and the upper layer of stirring blades are fixed to the stirring shaft; the upper layer of stirring blades are variable-cross-section type two-blade inclined blades; both the front edges and the rear edges of the main blades of the variable-cross-section type two-blade inclined blades are in sawtooth shapes. According to the stirring device, macromolecular gelatin materials can be dispersed, cut and broken effectively, the capacity of maintaining uniform, stable and rapid stirring is achieved, and the optimal stirring flow pattern is achieved, so that molecular weight distribution is effectively controlled, the percent of pass of subsequent products is raised, production time is saved, it can be further guaranteed that liquid medicine is prevented from splashing and hanging on the wall in the stirring process, accordingly the raw material loss is reduced, and production cost is saved.

Description

technical field [0001] The invention relates to the technical field of stirring devices, in particular to a stirring device and a container for preparing colloidal plasma solubilizers. Background technique [0002] Stirring, as the most commonly used mixing method in the industry, is a kind of circulation through the agitator, so that the gas, liquid and even suspended particles in the solution are mixed evenly. In order to achieve this purpose, it is necessary to use forced convection and uniform mixing devices. , that is, the stirring device, and the structure of the stirring device is closely related to the state, volume, density, viscosity, mixing requirements or reaction mechanism of the material to be stirred. [0003] For example, in the process of preparing colloidal plasma solubilizers, plasma solubilizers are also called plasma expanders, plasma expanders or plasma substitutes, and their application is an effective means of blood protection, which can achieve blood...

Claims

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Application Information

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IPC IPC(8): B01F7/18
CPCB01F27/071B01F27/074B01F27/172B01F27/112B01F27/192B01F27/90
Inventor 宋文慧
Owner 吉林省长源药业有限公司
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