Preparation of Propolis Liquid by Co-precipitation of Glycerol Monolinoleate

Abstract

The invention provides a glyceryl monolinoleate coprecipitation method for preparing propolis liquid, which solves the problem of dissolution rate of propolis and other bioactive components in the propolis can be kept to the maximum extent in a production process, used auxiliary materials can be widely applied to the production without limitation of a national standard use limit, the problem that after the auxiliary materials are used, side products unfavorable for a human body are generated or the auxiliary materials are unfavorable for the human body is solved, one big advantage of producing the propolis liquid by using a coprecipitation method is great reduction of residue of the propolis, practice shows that the residue of the propolis is only below 0.1% of the charged propolis, nearly no residue exists, the dissolution is thorough, a technical solution takes glyceryl monolinoleate as the auxiliary material and edible alcohol as a solvent, a precipitation technology is adopted to dissolve propolis in the glyceryl monolinoleate and forms a stable liquid state, and the alcohol is dried and recycled to obtain the propolis liquid.

Description

technical field [0001] The invention belongs to the field of preparation of health care products, and in particular relates to a method for preparing propolis liquid by adopting a co-precipitation method of glycerol monolinoleate. Background technique [0002] Propolis is listed in the Pharmacopoeia of the People's Republic of China. It is a kind of medicine that is difficult to dissolve in water. When producing products, in order to ensure that propolis can be effectively used by the human body, the problem of propolis dissolution must be solved. The active ingredients of propolis in propolis products must be in the Dissolution in water or gastric juice, that is, propolis must have good hydrophilicity. In my country, propolis belongs to the category of health food and drug management, and mainly exists in the form of health food. The dosage forms include propolis tablets, propolis capsules, propolis soft capsules, propolis liquid, etc. There are more than 400 health food ap...

AI Technical Summary

Problems solved by technology

[0013] The present invention is in order to solve the deficiencies in the prior art, the present invention provides a kind of production method that adopts glycerol monolinoleate coprecipitation method to prepare propolis liquid, it not only It solves the problem of the dissolution rate of propolis. At the same time, other bioactive components in propolis can be retained to the maximum extent during the production process. The excipients used can be widely used in production without being limited by the use limit of national standards. In addition to the above-mentioned problems that by-products that are harmful to the human body or that the auxiliary materials are harmful to the human body are easily produced after the use of auxiliary materials, the use of co-precipitation method to produce propolis liquid also has a major advantage of greatly reducing the amount of propolis residues. According to practice, the amount of propolis residues is only Less than 0.1% of the amount of propolis thrown, there is almost no residue, and the dissolution is more thorough