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1/3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on vascular wall

An intermittent, vascular wall technology, applied in the direction of the device introduced into the body, etc., can solve the problems of difficult operation and high cost consumption, and achieve the effect of simple operation, good scouring, and reducing blood turbulence.

Inactive Publication Date: 2016-05-11
TIANJIN UNIVERSITY OF TECHNOLOGY
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  • Application Information

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Problems solved by technology

This method is good, but the operation is very difficult and the cost is high

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  • 1/3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on vascular wall
  • 1/3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on vascular wall
  • 1/3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on vascular wall

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specific Embodiment approach

[0028] The specific implementation of the 1 / 3 intermittent single-pulse blood vessel perfusion method of the present invention is given below, including the following steps:

[0029] (1) Firstly, three-dimensional software is used for first-level vessel modeling, such as figure 1 , the middle bulge is a foreign body adhered to the blood vessel wall. Then import the vascular geometric model into the finite element analysis software for two-way fluid-structure interaction simulation. Two methods are used in the simulation process. The first step is to perfuse blood vessels with constant flow. Through the simulation, the angiodynamic parameters of constant flow perfusion will be obtained, and the perfusion quality will be evaluated to form a comparison item. The second step applies 1 / 3 intermittent single pulse flow for blood vessel perfusion. Likewise, the same angiodynamic parameters as constant flow perfusion, such as blood flow rate, shear force, etc., will be obtained thr...

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Abstract

The invention provides a 1 / 3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on the vascular wall. According to the method, pulsation and constant flow are combined, wherein the ratio of the pulsation perfusion time to the constant flow perfusion time within the single cycle is 3 to 1, and the pulsating flow enters the blood vessel in a periodic flow state for carrying out perfusion. The method comprises the following steps: (1) measuring the weight of the foreign matters in the blood vessel; (2) determining the surface intensity of pressure needed for impacting the foreign matters according to the obtained foreign matters, thus obtaining the perfusion speed; and (3) introducing the 1 / 3 time intermittent single pulsating flow into the blood vessel, observing the kinetic phenomenon of the blood vessel generated during the perfusion process through a medical means, and determining kinetic parameters of the blood vessel for evaluating the blood vessel perfusion quality according to the medical data. Finally, according the comparison of the two kinetic parameters of the blood vessel, the perfusion quality of blood vessel perfusion adopting the 1 / 3 time intermittent single pulsating flow is analyzed, thus the blood vessel perfusion is table, and meanwhile, the condition that the foreign matters are deposited on vascular wall is well improved, and the cleanness of the vascular wall is effectively improved.

Description

technical field [0001] The invention relates to a 1 / 3 intermittent single pulse flow perfusion method for reducing foreign matter deposition on the blood vessel wall, specifically a method for combining pulse flow and constant flow and performing blood vessel perfusion in a periodic blood flow state. Background technique [0002] The mortality rate induced by liver disease is very high in both developed and underdeveloped areas at home and abroad. Liver transplantation is currently the only effective means of treating end-stage liver disease. The quality of the liver donor is one of the key links affecting the success rate of liver transplantation. Cleaning (perfusion) of the liver donor before operation is a necessary medical procedure. Therefore, the quality of vascular perfusion directly affects the success of the operation. Many scholars at home and abroad have studied the process of vascular perfusion, analyzed the different phenomena and final effects of different vas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/14
CPCA61M5/14A61M2005/1402A61M2005/1403
Inventor 刘军王松丽陈建恩葛为民王肖锋刘懿禾刘增昌
Owner TIANJIN UNIVERSITY OF TECHNOLOGY
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