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Laminating rubber plug and production method thereof

A film-coated rubber stopper, rubber stopper technology, applied in the field of film-coated rubber stoppers and its production, can solve problems affecting drug safety, environmental pollution, rubber stopper penetration, etc., to ensure the uniformity of film extension, reduce puncture force, The effect of preventing rubber stopper from sticking

Inactive Publication Date: 2016-06-15
JIANGSU HUA LAN PHARMA NEW MATERIALS LTD BY SHARE LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to overcome the deficiencies in the prior art, the object of the present invention is to disclose a film-coated rubber stopper and its production method, so as to solve the problems of penetration, precipitation, and poor sealing of the existing rubber stopper when packaging and sealing injections; Direct contact with the plug affects the safety of the drug, clinical use of non-standard needle needles exceeds the standard and affects the safety of the drug, silicone oil causes pollution to the drug and affects the safety of the drug, and secondary vulcanization in the production process causes environmental pollution.

Method used

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  • Laminating rubber plug and production method thereof
  • Laminating rubber plug and production method thereof
  • Laminating rubber plug and production method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0025] Embodiment one: if figure 1 It is the top view of the coated rubber plug, figure 2 Schematic diagram of the cross-sectional structure of the coated rubber plug, image 3 As shown in the cross-sectional diagram of the combination of the film-coated rubber stopper and the packaging bottle, the rubber stopper includes a rubber stopper crown (1) and a rubber stopper neck (2). The rubber stopper neck (2) adopts a spherical arc surface design, and the rubber stopper The plug part (3) of the plug neck (2) is small at the top and large at the bottom, the bottom surface of the rubber plug neck (2) is a spherical arc surface, and the coating part of the film-coated rubber plug is designed with a spherical arc surface to ensure The uniformity of film extension, uniformity of thickness, and uniformity of drug shielding ensure the safety of the preparation. The design of the plug part (3) with a small upper part and a larger lower part can ensure that the plug will never jump duri...

Embodiment 2

[0026] Embodiment two: if figure 1 It is the top view of the coated rubber plug, figure 2 Schematic diagram of the cross-sectional structure of the coated rubber plug, image 3 As shown in the schematic cross-sectional view of the combination of the film-coated rubber stopper and the packaging bottle, a ring protrusion can also be provided around the needle-punched hole (5) in the film-coated rubber stopper. The ring protrusion is higher than the plane of the rubber plug, which not only prevents the rubber plug from sticking, but also facilitates the stability of the suction plug when the rubber plug is removed.

[0027] The production method of film-coated rubber stopper of the present invention, step is as follows:

[0028] Step 1. Extrusion

[0029] Use an extruder to extrude the mixed rubber material into a rubber sheet;

[0030] Step two, film

[0031] Put the rubber sheet extruded in step 1 on the film, press it, and then put the rubber sheet pressed with the film ...

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Abstract

The invention discloses a laminating rubber plug which comprises a rubber plug crown part and a rubber plug neck part, wherein the bottom surface of the rubber plug neck part is a spherical arc surface; the surface of the plug neck is covered with a film; the laminating part stretches from the surface of the plug neck to the plane position of the plug crown part sealed with a bottleneck; the plug column part of the rubber plug neck part has a small top and a big bottom; and spherical concave pinpricks are formed in the top surface of the rubber plug crown part, and protuberances are arranged around the pinpricks. The invention also discloses a production method of the laminating rubber plug, which comprises four steps of piece squeezing, piece punching, vulcanization and after-treatment. Due to the technical scheme, direct contact between the rubber plug and tablets can be prevented, the medicine is prevented from permeating and being precipitated and dissolved out for sure, the air tightness can be guaranteed, the plug jump can be avoided in automatic encapsulation, and exceeding fragmentation caused by a non-standard needle can be prevented; and moreover, secondary vulcanization is reduced in the production method, the silicification technology is not adopted, the materials and secondary pollution are reduced, and the original characteristics of the film materials are guaranteed.

Description

technical field [0001] The invention relates to a film-coated rubber stopper and a production method thereof, which are mainly used for packaging and sealing injection medicines. technical background [0002] When the existing rubber stoppers used for the packaging and sealing of injection medicines are used to seal the medicines, if the medicines are inverted at the mouth of the bottle, penetration and precipitation will occur, which will affect the safety of the medicines; the water injection medicines directly contact with the rubber stoppers, which will cause "penetration", " Substances such as "dissolution", "precipitation", "leaching", and "extractable" lead to a decrease in drug safety; the existing rubber stoppers used for injection drug packaging and sealing will cause needles to fall off when punctured with non-standard needles in clinical practice Exceeding the standard; in order to ensure the stability of high-speed packaging in the existing rubber stopper produc...

Claims

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Application Information

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IPC IPC(8): A61J1/14B29D99/00
CPCA61J1/14A61J1/1487B29D99/0096B29L2031/56
Inventor 华国平华一敏华智敏
Owner JIANGSU HUA LAN PHARMA NEW MATERIALS LTD BY SHARE LTD
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