Apparatus and method for treating biological slide sample

Abstract

The invention discloses an apparatus and method for treating a biological slide sample. The apparatus mainly comprises a detection assembly, a base, arm Z, arm Y and arm X and a sampling probe. It is possible to automatically, regularly and quantitatively add a sample according to detection process requirements and detection steps, automatically control heating and automatically control liquid perfusion and liquid drainage, so that a detection process is fully automated. When the slide sample requires thermal treatment, it is possible to perfuse a solution into a mounting cell and heat. In the thermal treatment process, the solution in a gap will be sucked in from a bottom gap of a slide assembly under capillary action for the purpose of automatic supply even when it volatilizes, thermal treatment is full and uniform, drying never occurs, the problem that traditional drying by heating easily causes volatilization and slide drying is solved, and the reliability and repeatability of a heating process are guaranteed. The reliability, repeatability and efficiency of the treatment of the biological slide sample can be improved, and a whole-course automatic process can be achieved.

Description

technical field [0001] The invention belongs to the field of biological sample processing, in particular to a device and method for processing biological slide samples. Background technique [0002] Immunohistochemistry is a technique for detecting characteristic proteins of tumors or pathogens in pathological specimens by using the characteristics of specific recognition of antigens and antibodies. This technology can not only detect the nature and quantity of pathogenic characteristic substances, but also because it can maintain the original shape of pathological tissue and detect in situ of the lesion, making it the most effective for the identification, diagnosis and guidance of clinical treatment of tumors and other diseases and one of the commonly used methods. [0003] The experimental steps and principles of immunohistochemistry are: 1) Pathological specimens are obtained through surgery, fixed in formalin, dehydrated in alcohol, embedded in paraffin, cut into tissu...

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Problems solved by technology

However, this patent cannot be processed in large batches, and because the structure needs to flip the slides and coverslips, the operation steps will reduce the efficiency and affect the processing effect. The coverslips are only covered after the specimens have been processed to a certain stage, and the coverslips are liquid-moving. , when the liquid needs to be drained or let go to the next reagent, the cover needs to be turned up and lifted, and the cover does not have the function of allowing the liquid to pass freely; the cover needs to be turned over and lifted, which makes it inconvenient to add reagents in the next step ; Can not cover the whole slide is not conducive to the processing effect

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