Pharmaceutical composition matched with thyroid cancer osseous metastasis radiotherapy

A technology for thyroid cancer and a composition, applied in the field of traditional Chinese medicine, can solve problems such as unsatisfactory effects, and achieve the effects of improving disease resistance, improving bone quality, and good patient compliance

Inactive Publication Date: 2016-07-27
QINGDAO CHENDA BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The means of modern medicine to treat bone metastases of tumors include chemotherapy, radiotherapy, surgery, radionuclides, bisphosphonates

Method used

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  • Pharmaceutical composition matched with thyroid cancer osseous metastasis radiotherapy
  • Pharmaceutical composition matched with thyroid cancer osseous metastasis radiotherapy
  • Pharmaceutical composition matched with thyroid cancer osseous metastasis radiotherapy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 capsule

[0036] Prescription: 25 parts of milk chai, 15 parts of bindweed root, 15 parts of dodder seed, 17 parts of rough yellow grass, 10 parts of black blood vine, 12 parts of deer ear feather, 9 parts of burden seven, 12 parts of Baijie vine, 16 parts of egg bald , 12 copies of the August letter.

[0037] Preparation method: (1) take Convolvulaceae root, Baijie vine, and August Zha according to the prescription, add 5 times the amount of 65% ethanol after crushing, reflux extraction twice, each time for 1.5 hours, filter, combine the two filtrates, and collect spinach After the ethanol extraction of flower root, Baijie vine, and August Zha, the residue is filtered, and the filtrate is decompressed to recover ethanol until it has no alcohol smell, and then concentrated under reduced pressure to obtain a dry extract, freeze-dried, and crushed to obtain an ethanol extract;

[0038] (2) Combine the filter residue after ethanol extraction of Convolvulaceae...

Embodiment 2

[0040] Embodiment 2 capsules

[0041] Prescription: 28 parts of milk chai, 16 parts of bindweed root, 12 parts of dodder seed, 15 parts of rough yellow grass, 12 parts of black blood vine, 10 parts of deer ear feather, 10 parts of burden seven, 8 parts of Baijie vine, 17 parts of egg bald , August letter 10 copies.

[0042] Preparation method: (1) According to the prescription, take Convolvulus root, Baijie vine, and August Zha, add 6 times the amount of 65% ethanol after crushing, reflux extraction twice, each time at 1.5 to 2.0 hours, filter, combine the two filtrates, Collect the filter residue after ethanol extraction of Convolvulaceae root, Lily vine, and Augustia, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, continue to concentrate under reduced pressure to form a dry extract, freeze-dry, and pulverize to obtain the ethanol extract;

[0043] (2) Combine the filter residue after ethanol extraction of Convolvulaceae root,...

Embodiment 3

[0045] Embodiment 3 capsules

[0046] Prescription: 30 parts of milk chai, 15 parts of bindweed root, 10 parts of dodder seed, 20 parts of rough yellow grass, 13 parts of black blood vine, 15 parts of deer ear feather, 10 parts of burden seven, 12 parts of Baijie vine, 13 parts of egg bald , August letter 10 copies.

[0047] Preparation method: (1) According to the prescription, take Convolvulaceae root, Baijie vine, and August Zha, add 3 to 8 times the amount of 65% ethanol after crushing, reflux extraction twice, each time for 1 to 3 hours, filter, and combine twice The filtrate is collected from the ethanol-extracted filter residue of Convolvulaceae, Baijie, and Augustia, and the filtrate is decompressed to recover ethanol until it has no alcohol smell, and is continuously concentrated under reduced pressure to form a dry extract, freeze-dried, and pulverized to obtain an ethanol extract;

[0048] (2) Combine the filter residue after ethanol extraction of Convolvulaceae ro...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine and particularly relates to a pharmaceutical composition matched with thyroid cancer osseous metastasis radiotherapy and a preparation method thereof. The pharmaceutical composition comprises ficus lyrata, calystegia sepium root, semen cuscutae, Dendrobium densiflorum Lindl ex Wall., sargentodoxa cuneata, winged laggera herb, dysosma difformis, radix cycleae hypoglaucae, Cantonese speranskia and Akebia trifoliata Koidz. The pharmaceutical composition matched with the thyroid cancer osseous metastasis radiotherapy has the advantages that the medicinal materials are combined to achieve synergic effects of tonifying the kidney and invigorating the bones, promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals and clearing away heat and toxic materials, the pharmaceutical composition can improve the blood circulation at affected parts, enhance bone density, relieve bone destruction and enhance the radiotherapy effect, and meanwhile, the pharmaceutical composition can regulate the physiological function of a body, increase immunity, effectively relieve symptoms such as excessively low leucocyte caused by the cancer radiotherapy, and increase the living quality of a patient.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition combined with radiotherapy for bone metastasis of thyroid cancer and a preparation method thereof. Background technique [0002] Thyroid cancer is a relatively common malignant tumor in the head and neck, accounting for 1% to 2% of systemic malignant tumors. It is more common in women and can be seen in any age group. At present, the incidence of thyroid cancer is increasing significantly year by year. "Surgery + iodine 131 therapy + thyroid hormone suppression" is recognized as the best comprehensive treatment plan for differentiated thyroid cancer (DTC), which can reduce the incidence of recurrence or metastasis. Although surgery combined 131 I treatment of DTC has achieved good curative effect, but the curative effect is not ideal after bone metastases. Increased clinical use 131 The method of I dosage improves clinical cu...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P35/04
CPCA61K36/185A61K36/28A61K36/29A61K36/39A61K36/47A61K36/486A61K36/59A61K36/60A61K36/898A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 陈令浩
Owner QINGDAO CHENDA BIOLOGICAL SCI & TECH
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