Compound glucose-reducing preparation containing phenformin and preparation method of compound glucose-reducing preparation

The technology of phenformin and compound prescription is applied in the field of compound hypoglycemic preparation containing phenformin and its preparation, which can solve problems such as side effects, and achieve the effects of balancing side effects, increasing blood sugar consumption, and strong antioxidant effect.

Inactive Publication Date: 2016-08-10
卢连伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the improvement of people's living standards, there are more and more patients suffering from diabetes. Diabetes is a disease that is difficult to cure. Patients need to take medicine and control diet for a long time. Drugs that are effective in treating diabetes, most of which are used to maintain the condition
These drugs have a certain therapeutic effect on diabetes, but they are also accompanied by many side effects, and long-term use will produce certain drug resistance and dependence.

Method used

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  • Compound glucose-reducing preparation containing phenformin and preparation method of compound glucose-reducing preparation
  • Compound glucose-reducing preparation containing phenformin and preparation method of compound glucose-reducing preparation

Examples

Experimental program
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Embodiment 1

[0017] Embodiment 1: A kind of compound hypoglycemic preparation containing phenformin, by weight component, comprises the composition of following parts by weight: 18 parts of phenformin, 145 parts of water-soluble dietary fiber, 40 parts of apovincine ethyl ester 29 parts of vitamin B1, 18 parts of gastric inhibitory peptide, 15 parts of glucodipeptide, 13 parts of benazepril, 12 parts of prostaglandin A1, 6 parts of sophoramethin, 2 parts of β-glucosidase, 1 part of chitosan oligosaccharide 1 part, 2 parts of indapamide, 1 part of curcumin, 1 part of sodium ferulate, and auxiliary materials: 2 parts of emulsifier, 0.1 part of preservative, and 0.04 part of antioxidant.

[0018] Wherein, the water-soluble dietary fiber is composed of fructo-oligosaccharides, isomalto-oligosaccharides, lacto-oligosaccharides, xylo-oligosaccharides, soybean oligosaccharides, agar powder, carboxymethyl cellulose according to the ratio of 9:8:7:6 :3:2:1 weight ratio; water-soluble dietary fiber ...

Embodiment 2

[0025] Embodiment 2: a kind of compound hypoglycemic preparation containing phenformin, by weight component, comprises the composition of following parts by weight: phenformin 26.5 parts, water-soluble dietary fiber 166 parts, apovincine ethyl ester 48 33.5 parts of vitamin B1, 21 parts of gastric inhibitory peptide, 18 parts of glucodipeptide, 15 parts of benazepril, 13 parts of prostaglandin A1, 8.5 parts of sophoramethin, 5.5 parts of β-glucosidase, 2.5 parts of chitooligosaccharide 3 parts, 3 parts of indapamide, 2 parts of curcumin, 1.5 parts of sodium ferulate, and auxiliary materials: 2.5 parts of emulsifier, 0.15 part of preservative, and 0.055 part of antioxidant.

[0026]Wherein, the water-soluble dietary fiber is composed of fructo-oligosaccharides, isomalto-oligosaccharides, lacto-oligosaccharides, xylo-oligosaccharides, soybean oligosaccharides, agar powder, carboxymethyl cellulose according to the ratio of 9:8:7:6 :3:2:1 weight ratio; water-soluble dietary fiber ...

Embodiment 3

[0033] Embodiment 3: A kind of compound hypoglycemic preparation containing phenformin, by weight component, comprises the composition of following parts by weight: phenformin 35 parts, water-soluble dietary fiber 187 parts, apovincine ethyl ester 56 parts 38 parts of vitamin B1, 24 parts of gastric inhibitory peptide, 21 parts of glucodipeptide, 17 parts of benazepril, 14 parts of prostaglandin A1, 11 parts of sophoramethin, 9 parts of β-glucosidase, 4 parts of chitosan oligosaccharide 4 parts, 4 parts of indapamide, 3 parts of curcumin, 2 parts of sodium ferulate, and auxiliary materials: 3 parts of emulsifier, 0.2 part of preservative, and 0.07 part of antioxidant.

[0034] Wherein, the water-soluble dietary fiber is composed of fructo-oligosaccharides, isomalto-oligosaccharides, lacto-oligosaccharides, xylo-oligosaccharides, soybean oligosaccharides, agar powder, carboxymethyl cellulose according to the ratio of 9:8:7:6 :3:2:1 weight ratio; water-soluble dietary fiber can ...

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PUM

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Abstract

The invention discloses a compound glucose-reducing preparation containing phenformin and a preparation method of the compound glucose-reducing preparation. The compound glucose-reducing preparation consists of the following components: the phenformin, water-soluble dietary fibers, vinpocetine, vitamin B1, gastric inhibitory peptide, glutamine dipeptide, benazepril, prostaglandin A1, sophorin A, beta-glucosidase, chitosan oligosaccharide, indapamide, curcumin and sodium ferulate. The compound preparation disclosed by the invention, on the basis of the combined action of various medicinal components, is capable of promoting secretion of insulin, so that the purpose of reducing glucose is achieved; the compound preparation is capable of effectively improving immunity of a patient and preventing various diabetic complications; and moreover, the compound preparation is significant in glucose-reducing effect, low in side effects and free from adverse effects on the patient in a long term of using, and the compound preparation has a broad application prospect.

Description

technical field [0001] The invention relates to the technical field of diabetes medication, in particular to a compound hypoglycemic preparation containing phenformin and a preparation method thereof. Background technique [0002] Diabetes is a common disease caused by the interaction of genetic and environmental factors. Clinically, hyperglycemia is the main sign. Typical cases of diabetes often show symptoms such as polyuria, polydipsia, polyphagia, and weight loss, that is, "three more and one less". Moreover, diabetes can easily cause complications such as cardiovascular disease, kidney disease, and neuropathy. Diabetes can cause damage to multiple systems in the body. It causes absolute or relative insufficient secretion of insulin and decreased sensitivity of target tissue cells to insulin, causing a series of metabolic disorder syndromes such as protein, fat, water and electrolyte, among which hyperglycemia is the main symbol. [0003] With the improvement of people...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61K9/08A61K47/34A61P3/10A61K31/155A61K31/702A61K31/4375A61K31/51A61K38/22A61K38/05A61K31/55A61K31/5575A61K36/489A61K31/7016A61K31/715A61K31/404A61K31/12A61K31/192A61K31/717
CPCA61K38/47A61K9/0095A61K31/12A61K31/155A61K31/192A61K31/404A61K31/4375A61K31/51A61K31/55A61K31/5575A61K31/7016A61K31/702A61K31/715A61K31/717A61K36/489A61K38/05A61K38/22A61K47/14C12Y302/01021A61K2300/00
Inventor 卢连伟
Owner 卢连伟
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