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Application of a kind of deuterium-depleted water in eye diseases

A technology of deuterium-depleted water and application, applied in the application field of deuterium-depleted water in eye diseases, can solve the problems of blindness, corneal epithelium shedding, aggravation of dry eye, eye fatigue, etc., to relieve visual fatigue and improve dry eye. Symptoms, eye fatigue relief effect

Active Publication Date: 2019-02-05
SICHUAN GOODDOCTOR PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the improvement of people's living standards, different types of eyewashes have appeared on the market. In order to maintain the sterility of eyewashes and prolong the validity period of eyewashes, most of them have added preservatives to ensure quality. These ingredients can change the microenvironment of the eyeball surface , destroy the ocular surface structure, damage the original tightly connected epithelial cell structure, and cause corneal epithelial shedding, defect, and erosion. In severe cases, corneal ulcers, corneal dissolution, and perforation may even cause blindness. Normal tear secretion function will degenerate, which will also aggravate the corresponding symptoms of dry eyes and eye fatigue

Method used

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  • Application of a kind of deuterium-depleted water in eye diseases
  • Application of a kind of deuterium-depleted water in eye diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The raw material water (natural water) is passed through the electrolytic cell, the hydrogen gas obtained from the cathode is washed and cooled, and then enters the hydrogen burner, and pure oxygen is introduced into the hydrogen burner for combustion reaction, and the water vapor obtained by the reaction is cooled-condensed , and finally go through filtration, microfiltration, fine filtration, and sterilization. After microbial testing meets the requirements, it can be filled to obtain deuterium-depleted water with a deuterium content of 1-135ppm. The specific deuterium content needs to be further measured.

[0017] The effect of deuterium-depleted water of the present invention will be further described by experiment below:

experiment example 2

[0018] Experimental example 2 Experimental research on the curative effect of deuterium-depleted water of the present invention on dry eye syndrome

[0019] 1. Experimental animals

[0020] Thirty-six 6-week-old Wistar healthy female rats weighed 160-190 g.

[0021] 2. Reagents

[0022] Scopolamine hydrobromide, PAS staining kit, phenol red cotton thread, sodium fluorescein, etc.

[0023] 3. Method

[0024] 3.1 Establishment of rat dry eye model

[0025] The 6-week-old Wistar healthy female rats were randomly divided into 6 groups, which were the normal control group and the model control group, and treated groups 1, 2, 3, and 4. Except for the normal control group, the rats were subcutaneously injected with normal saline at a dose of 0.5ml / time , 4 times / day, the lower limbs of the other 5 groups of rats were subcutaneously injected with scopolamine hydrobromide, the dose was 0.5ml / time, 4 times / day, and the lower limbs were carried out alternately; at the same time, the ...

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Abstract

The invention provides an application of deuterium-depleted water in dye diseases. The content of the deuterium-depleted water is 1-135ppm, preferably the content of deuterium is 50-80ppm and more preferably the content of the deuterium is 50ppm. The deuterium-depleted water disclosed by the invention, after sterilized, is applicable to dye drop treatment, and the deuterium-depleted water has a good effect on improving symptoms of dry eyes; meanwhile, the deuterium-depleted water can also take an effect on relieving visual fatigue caused by using eyes for a long time; and the deuterium-depleted water disclosed by the invention, which is free from any chemical additives, is free from side effects when used for eye care for a long time, and the deuterium-depleted water is relatively good in market application value.

Description

technical field [0001] The invention belongs to the field of eye care, in particular to the application of deuterium-depleted water in eye diseases. Background technique [0002] Nowadays, environmental problems are becoming more and more prominent. Exhaust gas emissions from chemical plants, vehicle exhaust emissions, smog, sandstorms, etc. will cause or aggravate eye discomfort. In addition, long-term wear of contact lenses and makeup will cause eye dryness, soreness, fatigue, foreign body sensation and other discomforts. Modern people stare at computer and mobile phone screens for a long time, especially in air-conditioned rooms, and eye moisture is more likely to be lost. , will produce dry eyes, conjunctival hyperemia, eye fatigue and other symptoms. [0003] But there is no eye care solution with high safety, good effect and suitable for public use in the market at present. With the improvement of people's living standards, different types of eyewashes have appeared ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/00A61P27/02
Inventor 刘越飞
Owner SICHUAN GOODDOCTOR PHARMA GRP
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