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A kind of capsule and preparation method thereof

A technology of capsules and capsules, which is applied in the field of medicine, can solve the problems of poor sealing of drugs, dangers brought by children, and short shelf life, and achieve the effects of not being brittle and disintegrating, shortening the absorption time, and improving the activity of enzymes

Active Publication Date: 2019-06-21
ZHEJIANG YILI CAPSULE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the capsules in the prior art tend to have the following defects: since the capsule cap and the capsule body are two independent parts, there must be a gap between the capsule body and the capsule cap, which makes the medicine in the capsule not tightly sealed and leads to shelf life. Short, it will also be mistaken for children to pull out the capsule body from the capsule cap and swallow the drug particles inside by mistake, which may even bring danger to children
Among them, if the small molecular protein-friendly compounds accumulated in the body are not removed, there is a risk of endangering health

Method used

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  • A kind of capsule and preparation method thereof
  • A kind of capsule and preparation method thereof
  • A kind of capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] refer to figure 1 , a capsule, comprising a capsule body, the capsule body comprising a capsule body 1 and a capsule cap 2, the capsule body 1 is sleeved in the capsule cap 2, a protective film 3 is provided outside the capsule body, the protection The membrane is an enteric coating, and a sealing belt 4 is provided at the joint of the capsule body 1 and the capsule cap 2 .

[0028] The inside of the capsule body is a cavity, and more than one partition 6 is arranged in the cavity, and the partition is arranged in the cavity of the capsule body 1, and the capsule body is provided with several draw-in slots 5, and the capsule body The clapboard in the cavity and the capsule body are clamped. The movable setting of the partition can adjust the size of the independent medicine compartment, which can facilitate the collocation and placement of different kinds of medicines in the capsule.

[0029] The capsule body is composed of the following components in parts by weight:...

Embodiment 2

[0038]Referring to Example 1 for the capsule structure, the capsule body is composed of the following components in parts by weight: 100 parts of corn starch, 3 parts of pectin sugar, 200 parts of deionized water, 2 parts of sodium alginate, 0.5 parts of calcium chloride, ten parts 0.5 part of sodium dialkyl sulfate; the sealing tape is made of hydroxypropyl methylcellulose.

[0039] The preparation method of above-mentioned capsule, comprises the steps:

[0040] (1) Dissolve calcium chloride and sodium lauryl sulfate in some deionized water, then add sodium alginate while stirring, then add the remaining deionized water to the above solution, and put the solution at 80-90°C Keep warm for 10 minutes, then add cornstarch and pectin sugar while stirring, and finally stir the prepared glue evenly, and let it stand for defoaming; among them, the stirring speed of the glue is 100r / min, and the stirring time is 3min, and stand for defoaming The temperature is controlled at 45°C;

...

Embodiment 3

[0047] Referring to Example 1 for the capsule structure, the capsule body is composed of the following components in parts by weight: 100 parts of cornstarch, 6 parts of pectin sugar, 300 parts of deionized water, 8 parts of sodium alginate, 1.5 parts of calcium chloride, ten parts 1.5 parts of dialkyl sodium sulfate, 2 parts of auxiliary materials; the auxiliary materials are glycerin, titanium dioxide, and food coloring, wherein, 0.6 parts of glycerin, 0.9 parts of titanium dioxide, and 0.5 parts of food coloring; the sealing tape is made of hydroxypropyl methyl Made of cellulose.

[0048] The preparation method of above-mentioned capsule, comprises the steps:

[0049] (1) Dissolve calcium chloride and sodium lauryl sulfate in some deionized water, then add sodium alginate while stirring, then add the remaining deionized water to the above solution, and put the solution at 80-90°C Keep warm for 10 minutes, then add cornstarch and pectin sugar while stirring, and finally sti...

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Abstract

The invention relates to a capsule and a preparation method thereof. The capsule comprises a capsule main body, wherein the capsule main body comprises a capsule body and a capsule cap, the capsule body is sheathed in the capsule cap, a protective film is arranged on the outer side of the capsule main body and is an enteric-soluble film coating, and a sealing band is arranged at the position where the capsule body and the capsule cap are sheathed and connected. The capsule is not only good in sealing property and high in safety, but also high in stability, free from interaction with drugs, good in compatibility, and difficult to harden, crisp and disintegrate; and the capsule can realize site-specific release in large intestine.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a capsule and a preparation method thereof. Background technique [0002] The current main structure of the existing capsule consists of two parts, namely the capsule body and the capsule cap. The capsule body and the capsule cap are U-shaped. The inner diameter of the opening side of the capsule cap matches the outer diameter of the capsule, so that the opening side of the capsule body can be inserted into the opening of the capsule cap. On the side, an inner cavity is formed for containing drug particles. However, the capsules in the prior art tend to have the following defects: since the capsule cap and the capsule body are two independent parts, there must be a gap between the capsule body and the capsule cap, which makes the medicine in the capsule not tightly sealed and leads to shelf life. Short, the capsule body will also be pulled out from the capsule cap b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K47/36A61J3/07
CPCA61J3/072A61K9/4816A61K47/36
Inventor 章国林
Owner ZHEJIANG YILI CAPSULE
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