Yixuanning capsule and preparation method thereof

A technology of Yixuanning and capsules, which is applied in the field of Yixuanning capsules and its preparation, can solve the problems of low content of active ingredients, large dosage for patients, inconvenient taking, etc., and achieve stable active ingredients, strong applicability, and effective ingredients. destroyed effect

Inactive Publication Date: 2016-11-09
南京多宝生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation method in the prior art has rough and backward process, many impurities, and low active ingredient content, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the clinical application of this product

Method used

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  • Yixuanning capsule and preparation method thereof
  • Yixuanning capsule and preparation method thereof
  • Yixuanning capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Stir-fried cocklebur seeds 20g, chrysanthemum 15g, Dannanxing 15g, skullcap 15g, bamboo rud 15g, calcined oyster 20g, hawthorn 10g, tangerine peel 15g, white peony 15g, pig iron 15g, tuckahoe 20g, wolfberry 20g, and the above twelve flavors , Add 10 times the weight of the medicinal material in water, soak for 0.5h, decoct for 1 hour, filter, add the medicinal residue to 8 times the weight of the medicinal material in water, decoct for 1 hour, filter out the medicinal liquid, combine the two decoctions, and concentrate to The relative density at 60°C is 1.05. Add ethanol to make the alcohol content 75% by volume. Stir, stand and filter. The filtrate is concentrated to 65°C and the relative density is 1.25. The ethanol is recovered to obtain a concentrated solution. Supercritical extraction is used. , Obtain the supercritical extract, continue to concentrate, dry the concentrate, granulate, and fill the capsule to obtain Yixuanning capsule.

[0022] In the preparation metho...

Embodiment 2

[0032] Stir-fried cocklebur seeds 20g, chrysanthemum 15g, Dannanxing 15g, skullcap 15g, bamboo rud 15g, calcined oyster 20g, hawthorn 10g, tangerine peel 15g, white peony 15g, pig iron 15g, tuckahoe 20g, wolfberry 20g, and the above twelve flavors , Add 10 times the weight of the medicinal material in water, soak for 0.5h, decoct for 1 hour, filter, add the medicinal residue to 8 times the weight of the medicinal material in water, decoct for 1 hour, filter out the medicinal liquid, combine the two decoctions, and concentrate to The relative density at 60°C is 1.05. Add ethanol to make the alcohol content 75% by volume. Stir, stand and filter. The filtrate is concentrated to 65°C and the relative density is 1.25. The ethanol is recovered to obtain a concentrated solution. Supercritical extraction is used. , Obtain the supercritical extract, continue to concentrate, dry the concentrate, granulate, and fill the capsule to obtain Yixuanning capsule.

[0033] In the preparation metho...

Embodiment 3

[0036] Stir-fried cocklebur seeds 20g, chrysanthemum 15g, Dannanxing 15g, skullcap 15g, bamboo rud 15g, calcined oyster 20g, hawthorn 10g, tangerine peel 15g, white peony 15g, pig iron 15g, tuckahoe 20g, wolfberry 20g, and the above twelve flavors , Add 10 times the weight of the medicinal material in water, soak for 0.5h, decoct for 1 hour, filter, add the medicinal residue to 8 times the weight of the medicinal material in water, decoct for 1 hour, filter out the medicinal liquid, combine the two decoctions, and concentrate to The relative density at 60°C is 1.05. Add ethanol to make the alcohol content 75% by volume. Stir, stand and filter. The filtrate is concentrated to 65°C and the relative density is 1.25. The ethanol is recovered to obtain a concentrated solution. Supercritical extraction is used. , Obtain the supercritical extract, continue to concentrate, dry the concentrate, granulate, and fill the capsule to obtain Yixuanning capsule.

[0037] In the preparation metho...

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Abstract

The invention provides a preparation method of a Yixuanning capsule. The preparation method comprises the following steps of taking 20g of fried fructus xanthii, 15g of flos chrysanthemi, 15g of bile arisaema, 15g of radix scutellariae, 15g of caulis bambusae in taeniam, 20g of calcined oyster shell, 10g of fructus crataegi, 15g of pericarpium citri reticulatae, 15g of radix paeoniae alba, 15g of ferrosic oxide, 20g of poria cocos and 20g of fructus lycii; adding water of which the weight is ten times that of the twelve medicinal materials; adopting specific concentrating and drying equipment. The content of total glucosides of radix paeoniae alba in the prepared Yixuanning capsule is high; the Yixuanning capsule is found to be applied in preparation of medicines for suppressing african green monkey kidney Vero-E6 cell proliferation.

Description

Technical field [0001] The invention relates to the technical field of Chinese medicine extraction, in particular to a Yixuaning capsule and a preparation method thereof. Background technique [0002] Yixuanning Capsules can calm the liver and suppress yang, reduce fire and phlegm, nourish blood and invigorate the spleen, dispel wind and clear heat, and cure vertigo with hyperactivity of liver yang and deficiency of both Qi and blood. The preparation method in the prior art has rough and backward technology, many impurities, and low content of active ingredients, which leads to excessive dosage for patients and inconvenience to take, which seriously affects the clinical application of the product. Summary of the invention [0003] Objective of the invention: In order to solve the above-mentioned problems, the objective of the present invention is to provide a Yixuanning capsule and a preparation method thereof. [0004] Technical Solution: The purpose of the present invention is ac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/48A61P1/08A61P43/00A61K35/618A61K33/26
CPCA61K36/899A61K9/16A61K33/26A61K35/618A61K36/076A61K36/28A61K36/287A61K36/539A61K36/65A61K36/71A61K36/734A61K36/752A61K36/815A61K36/8884A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 李洋
Owner 南京多宝生物科技有限公司
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