Production method of low-solvent residue rhizoma curcumae longae extract

A production method and technology of turmeric are applied in the production field of low-dissolving residual turmeric extract, can solve the problems of affecting the normal use of curcumin, harm to human health, and high solvent residues, achieve optimization of vacuum desolventizing and residual technology, and reduce crystallization speed. , the effect of short desolvation residual time

Active Publication Date: 2016-12-07
CHENGUANG BIOTECH GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, organic solvent extraction is mainly used to extract active ingredients from turmeric. Generally, methanol or ethanol is selected as an extraction solvent. First, turmeric is ground into powder, then added to solvent extraction, and then filtered and concentrated. The active ingredient is turmeric extract, curcumin in turmeric extract is easy to form crystals, and forms a state of encapsulation to the solvent, which makes it difficult to remove the solvent
It is difficult to further reduce the solvent residues in turmeric extract by using conventional solvent removal methods. At present, the total solvent residues of turmeric extracts in the industry (including all detectable solvent residues such as ethanol and acetone) are around 1000-5000ppm, and some Even Higher, Higher Solvent Residual Turmeric Extract Potentially Hazardous to Human Health as a Food Additive
At the same time, due to the high solvent residue in turmeric extract, the curcumin refined from it as a raw material has a relatively high dissolved residue, which directly affects the normal use of curcumin as a food additive.
[0004] At present, there are basically no reports on the literature on reducing solvent residues in turmeric extract. Therefore, it is urgent to develop a low-solvent residue turmeric extract production method in the industry to improve the safety of curcumin as a food additive.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] (1) Take 1 kg of turmeric powder raw material (curcumin content 7.0%), add acetone for extraction, extraction temperature is 45°C, add 5 L of acetone each time, soak for 1 hour, and extract 7 times. The extracts were combined and filtered.

[0025] (2) Evaporate the filtered extract under the conditions of vacuum 0.05Mpa and temperature 70°C to recover the solvent. When there is no condensate in the condenser tube, stop the evaporation to obtain 0.37kg of crude extract of turmeric extract.

[0026] (3) Add 11.1 g of hydrochloric acid aqueous solution with a mass concentration of 0.5% to the crude extract of turmeric extract.

[0027] (4) Under the condition of vacuum degree of 0.09Mpa and temperature of 95°C, nitrogen gas at 100°C must be introduced into the material, and the time of solvent removal is 1 hour to obtain 0.25kg of turmeric extract (curcumin Content 27.5%), content yield 98.2%.

Embodiment 2

[0029] (1) Take 1kg of turmeric powder raw material (curcumin content 7.0%), add acetone for extraction, extraction temperature is 40°C, add 10L of acetone each time, soak for 0.75h, and extract 5 times. The extracts were combined and filtered.

[0030] (2) Evaporate the filtered extract under the conditions of vacuum 0.05Mpa and temperature 69°C to recover the solvent. When there is no condensate in the condenser tube, stop the evaporation to obtain 0.42kg of crude extract of turmeric extract.

[0031] (3) Add 12.6 g of acetic acid aqueous solution with a mass concentration of 1% to the crude extract of turmeric extract.

[0032] (4) Under the conditions of vacuum degree of 0.095Mpa and temperature of 85°C, nitrogen gas at 80°C must be introduced into the material, and the time of solvent removal is 3 hours to obtain 0.28kg of turmeric extract (curcumin) with a total dissolved residue of 5ppm Content 24.6%), content yield 98.4%.

Embodiment 3

[0034] (1) Take 1 kg of turmeric powder raw material (curcumin content 6%), add acetone for extraction, the extraction temperature is 42°C, add 8L of acetone each time, soak for 0.5h, and extract 6 times. The extracts were combined and filtered.

[0035] (2) Evaporate the filtered extract under the conditions of vacuum 0.055Mpa and temperature 69°C to recover the solvent. When there is no condensate in the condenser tube, stop the evaporation to obtain 0.38kg of crude extract of turmeric extract.

[0036] (3) Add 11.4 g of hydrochloric acid aqueous solution with a mass concentration of 0.7% to the crude extract of turmeric extract.

[0037] (4) Under the conditions of vacuum degree 0.093Mpa and temperature 90°C, nitrogen gas at 90°C must be introduced into the material, and the time for solvent removal is 2 hours to obtain 0.25 kg of turmeric extract (curcumin Content 23.7%), content yield 98.75%.

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Abstract

The invention discloses a production scheme of low-solvent residue rhizoma curcumae longae extract. The production scheme comprises the following steps of adding an acid solution in a to-be-processed rhizoma curcumae longae extract crude extract, and carrying out solvent residue removing operation, thus obtaining the low-solvent residue rhizoma curcumae longae extract. The production scheme disclosed by the invention is simple in technology and convenient to operate, the total solvent residue in obtained rhizoma curcumae longae extract is effectively removed to below 10ppm, and the safety of the rhizoma curcumae longae extract which is used as a food additive is increased.

Description

technical field [0001] The invention belongs to the technical field of natural extracts, and in particular relates to a production method of turmeric extract with low solvent residue. Background technique [0002] Turmeric is a perennial herb of Zingiberaceae. It is a traditional medicinal material with the same source of medicine and food. The curcumin contained in turmeric can not only be used as a natural pigment, but also has anti-inflammatory, anti-cancer, anti-oxidation, antibacterial, Antiviral and other physiological functions have obvious effects on the treatment of various diseases. [0003] At present, organic solvent extraction is mainly used to extract active ingredients from turmeric. Generally, methanol or ethanol is selected as an extraction solvent. First, turmeric is ground into powder, then added to solvent extraction, and then filtered and concentrated. The active ingredient is turmeric extract, curcumin in turmeric extract is easier to form crystals, an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L5/43A23L5/20
Inventor 齐立军褚延伟魏占姣季绍东边媛媛
Owner CHENGUANG BIOTECH GRP CO LTD
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