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Pharmaceutical composition used for treating cancer pain for anesthesia department

A cancer pain and composition technology, which is applied in the field of pharmaceutical compositions for the treatment of cancer pain, can solve the problems of poor cancer pain effect, inability to use for a long time, drug dependence, etc., achieve great clinical promotion value, and improve immunity. , the effect of reducing discomfort

Inactive Publication Date: 2016-12-28
罗艳华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Chronic cancer pain is chronic pain caused by malignant tumors. Among the subjective symptoms of cancer patients, the incidence of pain is the highest; 25-40% of newly diagnosed malignant tumor patients, 30-50% of cancer patients during active treatment, 70%- 90% of patients will have this symptom in the advanced stage of cancer. Many cancer patients have to endure the great pain of cancer pain in the last period of life. Drug therapy is the main method of cancer pain treatment. Anesthesiology currently treats cancer pain The methods of local treatment, analgesics to block the conduction pathway of pain, etc.; the current analgesics include aspirin, analgesic, analgin, indomethacin, etc., but the curative effect on cancer pain is not good, night work gastrointestinal reactions and Bone marrow suppression and other side effects cannot be used for a long time; anesthesia analgesics include codeine and pethidine, although they temporarily relieve cancer pain, they are easy to cause drug dependence, and the demand is increasing, and the interval time is getting shorter and shorter; Based on the above reasons, it is necessary to develop new anesthetic drugs for the treatment of cancer pain to meet the needs of cancer patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A pharmaceutical composition used in the anesthesiology department for treating cancer pain, which is made of the following raw materials in parts by weight: 10 parts of Albizia Julibrissin, 15 parts of Jianweifeng, 4 parts of perilla leaves, 6 parts of Liangmianzhen, and Jiuxiangworm 4 parts, 5 parts of Duhuo, 4 parts of Luzon fruit, 10 parts of Panax notoginseng, 8 parts of Tianxianzi, 7 parts of annatto, 4 parts of borax, and 1 part of rat woman.

[0036] The preparation method of the pharmaceutical composition for the treatment of cancer pain in the department of anesthesiology comprises the following steps:

[0037] 1) Weigh each raw material according to the formula, wash and dry for later use;

[0038] 2) Grind Jiuxiang worm, borax, ratwort and Panax notoginseng into 400-600 mesh fine powder, and soak in an ethanol solution with 3 times the weight of the mixed fine powder and a volume fraction of 95% for 20 hours, and use CO 2 Supercritical extraction technology...

Embodiment 2

[0043] A pharmaceutical composition used in the anesthesiology department for treating cancer pain, which is made of the following raw materials in parts by weight: 20 parts of Albizia Julibrissin, 25 parts of Jianweifeng, 10 parts of Perilla leaves, 12 parts of Liangmianzhen, Jiuxiangworm 8 parts, 15 parts of Duhuo, 8 parts of Luzon fruit, 20 parts of Panax notoginseng, 12 parts of Tianxianzi, 13 parts of Hongmuxiang, 6 parts of borax, and 5 parts of rat woman.

[0044] The preparation method of the pharmaceutical composition for the treatment of cancer pain in the department of anesthesiology comprises the following steps:

[0045] 1) Weigh each raw material according to the formula, wash and dry for later use;

[0046] 2) Grind jiuxiangworm, borax, ratwort, and notoginseng into 600-mesh fine powder, and soak in an ethanol solution with 5 times the weight of the mixed fine powder and a volume fraction of 95% for 30 hours, and use CO 2 Supercritical extraction technology sep...

Embodiment 3

[0051] A pharmaceutical composition used in the anesthesiology department for treating cancer pain, which is made of the following raw materials in parts by weight: 13 parts of Albizia Julibrissin, 18 parts of Jianweifeng, 6 parts of Perilla leaves, 8 parts of Liangmianzhen, and Jiuxiangworm 5 parts, 9 parts of Duhuo, 5 parts of Luzon Fruit, 11 parts of Panax notoginseng, 9 parts of Tianxianzi, 9 parts of Hongmuxiang, 4 parts of Borax, and 2 parts of Ratwort.

[0052] The preparation method of the pharmaceutical composition for the treatment of cancer pain in the department of anesthesiology comprises the following steps:

[0053] 1) Weigh each raw material according to the formula, wash and dry for later use;

[0054] 2) Grind jiuxiang worm, borax, ratwort and notoginseng into 400-mesh fine powder, and soak in an ethanol solution with 3 times the weight of the mixed fine powder and a volume fraction of 95% for 24 hours, and use CO 2 Supercritical extraction technology separa...

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PUM

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Abstract

The invention discloses a pharmaceutical composition used for treating cancer pain for an anesthesia department. The pharmaceutical composition comprises the following raw materials in parts by weight: 10-20 parts of silktree flower, 15-25 parts of longestapex beautyberry leaves, 4-10 parts of perilla leaf, 6-12 parts of Zanthoxylum nitidum, 4-8 parts of aspongopus, 5-15 parts of levisticum, 4-8 parts of Strychnos ignatii, 10-20 parts of pseudo-ginseng, 8-12 parts of semen hyoscyami, 7-13 parts of scentedros wood, 4-6 parts of borax, and 1-5 parts of pillworm. The pharmaceutical composition has the advantages of proper compatibility of the raw materials, accords with compatibility between monarch and ministerial drug by science of Chinese pharmacology and modern pharmacology, has efficacy for clearing heat and detoxifying, activating blood circulation to dissipate blood stasis, rectifying qi and relieving pain, and removing toxicity for detumescence, can effectively alleviate ache, has advantages of good curative effect, no side effect, no drug dependence, and low drug usage cost, can directly reach the focus position, enhances cancer treatment effect, reduces discomfortableness of the patients during a treatment process, increases the patient immunity, and has great clinical popularization value.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition used in the anesthesiology department for treating cancer pain. Background technique [0002] Chronic cancer pain is chronic pain caused by malignant tumors. Among the subjective symptoms of cancer patients, the incidence of pain is the highest; 25-40% of newly diagnosed malignant tumor patients, 30-50% of cancer patients during active treatment, 70%- 90% of patients will have this symptom in the advanced stage of cancer. Many cancer patients have to endure the great pain of cancer pain in the last period of life. Drug therapy is the main method of cancer pain treatment. Anesthesiology currently treats cancer pain The methods of local treatment, analgesics to block the conduction pathway of pain, etc.; the current analgesics include aspirin, analgesic, analgin, indomethacin, etc., but the curative effect on cancer pain is not good, night work gastroi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61P35/00A61P29/00A61K33/22A61K35/63A61K35/64
CPCA61K36/48A61K33/22A61K35/63A61K36/232A61K36/258A61K36/535A61K36/56A61K36/57A61K36/758A61K36/79A61K36/81A61K36/85A61K2236/331A61K2236/37A61K2236/39A61K2300/00
Inventor 罗艳华
Owner 罗艳华
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