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Traditional Chinese medicine composition for treating angeitis and preparation method thereof

A composition and technology for vasculitis, applied in the field of medical preparations, can solve problems such as conservative treatment only, and achieve the effects of preventing recurrence of vasculitis, excellent curative effect and low cost

Inactive Publication Date: 2017-01-18
青岛友诚高新技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although modern medical science is very developed, it can only be treated conservatively, or surgical amputation, which brings many impacts on patients' life, work, and economy.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) a kind of Chinese medicine for the treatment of vasculitis is formed by the proportioning of following crude drugs by weight:

[0034] 30 parts of chicken blood seven, 25 parts of inverted berry, 20 parts of Yuanhu, 15 parts of phoenix grass, 15 parts of white ploughhead grass, 10 parts of jackal camphor, 10 parts of chicken feet, 10 parts of Baiyun flower root, large folic acid 10 parts of rattan, 5 parts of white uncaria, 5 parts of astragalus.

[0035] (2) Preparation method:

[0036] In the first step, the inverted berry and Yuanhu are mixed in proportion, extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then Purify 1-2 times with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize int...

Embodiment 2

[0041](1) a kind of Chinese medicine for the treatment of vasculitis is formed by the proportioning of following crude drugs by weight: with embodiment 1.

[0042] (2) Preparation method:

[0043] In the first step, the inverted berry and Yuanhu are mixed in proportion, extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then Purify once with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0044] The second step is to extract 2 times with the n-propanol of 80% alcohol concentration, extracting the extracts, concentrating under reduced pressure, drying, and pulverizing into powder. The pulverized powder is dissolved in water which is 2 times of its mass, rested for 1 hour, filtered, th...

Embodiment 3

[0048] 1. Long-term toxicity test process:

[0049] Apply Wistar rats (Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. provides) experimental medicine is set to high, medium and low three dosages, be respectively the capsule 8g / kg, 4g / kg, 2g of embodiment 1 formula / kg. Calculated according to the human dose of 0.1g / kg / day tablet, it is 80 times, 40 times and 20 times of the effective dose for human respectively; another control group is set up, which is given continuously for 90 days and 180 days by intragastric administration and part of the animals are withdrawn for 10 days. Days later, the effects on various physiological and biochemical indicators of rats were observed. The experimental results show that: continuous oral administration of different doses to rats for 180 days has no effect on the food intake and weight growth of the rats. No significant toxic effects were found on liver and kidney function. There was no obvious effect on blood routine, bl...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating angeitis. The traditional Chinese medicine comprises Chinese amphibious knotweed rhizome, ubus parvifolius, rhizoma corydalis, coniogramme japonica, viola alata burgsd, litsea rotundifolia, chicken's-claw wind, heracleum repula, embelia longifolia, uncariasessilifructus and radix astragali. The invention further discloses a method for preparing the traditional Chinese medicine composition. The traditional Chinese medicine composition has the advantages of being good in curative effect, low in cost, high in cure rate and free of adverse reaction and the like in the aspect of treating angeitis. The traditional Chinese medicine composition can promote blood circulation to remove blood stasis and dredge the channel and have a better curative effect than a product for treating angeitis diseases on the market at present, can further effectively prevent angeitis recurrence and is remarkable in effect.

Description

technical field [0001] The invention relates to a medical preparation, in particular to a traditional Chinese medicine composition for treating vasculitis and a preparation method thereof. Background technique [0002] The full name of vasculitis is "thromboangiitis obliterans". It is an allergic inflammation that occurs in blood vessels, leading to segmental stenosis and occlusion of small and medium arteries, loss of nutrition, ulceration, and necrosis at the extremities. It is a relatively stubborn vascular disease. Disease is not an inflammatory manifestation of the blood vessel wall itself, and has nothing to do with bacterial infection. In traditional Chinese medicine, thromboangiitis obliterans is classified into the category of "necrosis". There are records on the etiology, prognosis and treatment of gangrene. In addition to oral Chinese medicine, there are also treatments such as acupuncture, fumigation and external medicine powder. Although modern medical science...

Claims

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Application Information

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IPC IPC(8): A61K36/86A61P9/14
CPCA61K36/86A61K36/11A61K36/185A61K36/23A61K36/481A61K36/54A61K36/66A61K36/704A61K36/73A61K36/74A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 不公告发明人
Owner 青岛友诚高新技术有限公司
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