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Traditional Chinese medicine combination for treating chronic hepatitis with hepatic fibrosis and liver cirrhosis

A technology of hepatitis liver fiber and composition, applied in the field of traditional Chinese medicine composition, can solve the problems of low curative effect, large adverse reaction, limited to the experimental research stage, etc., and achieves the effect of good curative effect and excellent therapeutic effect

Inactive Publication Date: 2017-02-01
DALIAN BORUISEN BIOMEDICAL TECH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the gradual elucidation of the pathogenesis of liver fibrosis, treatment becomes possible, but there is no good treatment drug in Western medicine at present, colchicine, pentoxifylline, etc. have low curative effect and large adverse reactions, which are mostly limited to the experimental research stage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1 mixture

[0018] Prescription: 6 parts of Astragalus, 5 parts of Codonopsis, 5 parts of Angelica, 6 parts of Paeoniae Alba, 4 parts of Curcuma, 6 parts of Salvia, 8 parts of Turtle Shell, 2 parts of Turtle Shell, 4 parts of Millet Spatholobus, 6 parts of Sanleng, Curcuma 4 parts, 3 parts of peach kernel.

[0019] Preparation method: Add the above medicines, decoct twice with water, 1-3 hours each time, combine the decoctions, filter, and concentrate the clarified filtrate to a relative density of 1.05-1.10, add preservatives, and fill to obtain the mixture.

Embodiment 2

[0020] Embodiment 2 Granules

[0021] Prescription: 4 parts of Astragalus, 6 parts of Codonopsis, 5 parts of Angelica, 6 parts of Paeoniae Alba, 4 parts of Curcuma, 4 parts of Salvia, 6 parts of Turtle Shell, 2 parts of Turtle Shell, 6 parts of Millet Spatholobus, 6 parts of Sanleng, Curcuma 5 parts, 5 parts of peach kernel.

[0022] Preparation method: decoct the above drugs twice with water, 1-3 hours each time, combine the decoction, filter, concentrate the filtrate, extract the thick paste, dry under reduced pressure, crush to obtain dry extract powder, add paste according to the conventional process Essence and sucrose powder, mixed evenly, and made into granules.

Embodiment 3

[0023] Example 3 tablet

[0024] Prescription: 8 parts of Astragalus, 4 parts of Codonopsis, 4 parts of Angelica, 6 parts of Radix Paeoniae Alba, 4 parts of Turmeric, 4 parts of Salvia, 2 parts of Turtle Shell, 4 parts of Turtle Shell, 6 parts of Millet Spatholobus, 5 parts of Sanleng, Curcuma 5 parts, 5 parts of peach kernel.

[0025] Preparation method: add the above medicines, decoct twice with water, 1-3 hours each time, combine the decoctions, filter, concentrate the filtrate, extract thick paste, dry under reduced pressure, crush to obtain dry extract powder. Take the above dry extract powder, add talcum powder and compressible starch according to the conventional process, mix evenly, and press into tablets to obtain.

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PUM

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Abstract

Provided is a traditional Chinese medicine combination for treating chronic hepatitis with hepatic fibrosis and liver cirrhosis. The medicine combination consists of 12 traditional Chinese medicine constituents, radix astragali, radix condonopsis, angelica sinensis, radix paeoniae alba, radix curcumae, salvia miltiorrhiza, turtle shell, tortoiseshell, caulis spatholobi, rhizome sparganii, curcuma zedoary, peach kernel and more. The medicine combination can be prepared into various oral preparations such as health care product, food product, admixture, pills, tablets, capsules, granules and more. The traditional Chinese medicine combination is clinically proved to have outstanding treatment effects on patients with a variety of hepatoses, especially on patients with chronic hepatitis accompanied by fibrotic lesions or liver cirrhosis not accompanied by hemorrhagic tendencies. The traditional Chinese medicine combination employs traditional Chinese medicine treatment theory; patients are diagnosed and treated by arguments of blood stasis due to stagnation of qi, hepatic stagnation causing splenic deficiency, hypofunctioning of spleen and stomach, hepatic and renal yin deficiency, toxin generated by accumulation of damp heat, and others. The traditional Chinese medicine combination starts with etiology and pathogenesis, and treats with soothing liver and strengthening spleen, promoting qi to activate blood, dissolving stasis and eliminating symptoms, nourishing liver and kidney, cooling blood and eliminating stasis. The traditional Chinese medicine combination has a good clinical curative effect on symptoms like hepatitis fibrosis and liver cirrhosis.

Description

technical field [0001] The invention discloses a traditional Chinese medicine composition for treating chronic hepatitis liver fibrosis and liver cirrhosis, which belongs to the technical field of traditional Chinese medicine compositions. Background technique [0002] The total incidence of hepatitis has always ranked first among all kinds of infectious diseases in my country. Viral hepatitis, especially hepatitis B (HBV), is widely prevalent in my country and seriously endangers human health. It is one of the most prominent public health problems in my country at this stage. Currently, there are about 120 million hepatitis B virus carriers in my country, and about 20% of those infected become chronic carriers or hepatitis B patients. In the pathogenesis of chronic hepatitis, liver damage is caused by immune response, and persistent virus infection leads to chronicity, fibrosis and even liver cirrhosis and liver cancer. Hepatitis Liver fibrosis is a pathological process ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61K35/586
CPCA61K35/586A61K36/232A61K36/344A61K36/481A61K36/486A61K36/537A61K36/65A61K36/71A61K36/736A61K36/902A61K36/9066A61K2236/331A61K2236/39A61K2300/00
Inventor 何军曹云峰刘维红洪沫王志芹宋丹孙晓宇董军常东岳
Owner DALIAN BORUISEN BIOMEDICAL TECH CO LTD
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