A method of using a hollow-core electrospinning nozzle

Abstract

The invention provides a use method of a hollow-core electrostatic spinning nozzle. The nozzle in use is composed of an inner needle tube, an outer needle tube and a hollow tube. A needle opening is machined in the inner needle tube, is perpendicular to the axial direction of the inner needle tube and transversely penetrates through the inner diameter of the inner needle tube, and the surface of the needle opening is subjected to surface treatment. The hollow tube is coaxially installed in the inner needle tube. The hollow tube and the inner needle tube are coaxially installed in the outer needle tube. The use method includes the steps that firstly, according to properties of solutions used in an experiment, the inner needle tube, the outer needle tube and the hollow tube are cleaned with solvent or deionized water; secondly, a liquid supply system of the inner needle tube or the outer needle tube is opened, a nitrogen valve of the hollow tube is opened, and the flow speed is adjusted; thirdly, electrostatic spinning parameters are set; fourthly, after spinning, the nozzle is cleaned and dried for use. The nozzle has the advantages that mixed electrostatic spinning of two or more solutions with different components can be achieved, great convenience is brought to processing functional fiber materials of core-shell structures and porous structures, the nozzle can be widely used in the fields of medicine sustained release, tissue engineering, medicine carriers and the like and can be operated according to a single-needle-tube nozzle, and the operation process is simple.

Description

technical field [0001] The invention relates to a method for using an electrospinning nozzle. In terms of use, it is a method for using a hollow electrospinning nozzle for obtaining hollow or porous composite fibers based on an electrospinning method. Background technique [0002] The coaxial electrospinning method is a process developed by improving the device on the basis of electrospinning. It can be used to prepare fiber materials with special functional structures. deficiencies that existed. The common electrospinning device is a single-channel needle, while the coaxial electrospinning device contains two coaxial compound needles inside and outside. The two pipes of the compound needle are respectively connected to the syringe, and the syringe is controlled by a syringe pump to obtain a constant injection volume. , the inner and outer syringe solutions are respectively loaded into different syringes, driven by the syringe pump, the inner and outer syringe solutions flo...

AI Technical Summary

Problems solved by technology

[0003] However, due to the coaxial electrospinning nozzle and the strict operating process, it is not easy to control the formation of double-layer or composite fibers, especially the distance from the inner needle pipe to the outer needle pipe is the key factor affecting the formation of the coaxial jet flow Factors: If the distance is too small, the solution in the inner needle pipeline is easily blocked by the solution in the outer pipeline, and the inner needle solution cannot flow out smoothly. At this time, the inner solution cannot be stretched under the action of the electric field force, and only the outer solution is formed jet stream

When the distance is too large, the solution will flow out along the outer surface of the inner needle tube wall, and the protruding part of the inner needle cannot be completely covered, resulting in a lot of solution ejected from around the needle, and a stable coaxial jet flow cannot be obtained

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