Method for constructing allergic rhinitis model in non-human mammal by using pollen of Cryptomeria fortunei
A non-human mammal, allergic rhinitis technology, applied in the field of constructing non-human mammal allergic rhinitis model using cedar pollen, can solve the problems of lower respiratory tract sensitization, easy to cause asthma, etc. The effect of high rate and high model survival rate
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[0027] In order to illustrate the embodiments of the present invention or the technical solutions in the prior art more clearly, the drawings required in the description of the embodiments or the prior art will be briefly introduced below.
[0028] The invention provides a method for constructing a non-human mammalian allergic rhinitis model, using a Cryj1 solution for local sensitization and stimulation through the nose.
[0029] The method for constructing non-human mammal allergic rhinitis model provided by the embodiments of the present invention figure 1 ):
[0030] Step 1. Instill a solution containing Cryj1 into the nasal cavity of a non-human mammal every two weeks from the first day, for a total of four times;
[0031] Step 2. After the fourth exposure, the solution containing Cryj1 was dripped into the nasal cavity of non-human mammals every two days for a total of four times.
[0032] The specific implementation steps of this method are: weigh the BALB / c mice requ...
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